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Table 1 Characteristics of the patients with Kawasaki disease and Healthy control

From: The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease

CharacteristicsKawasaki diseaseHealthy Control
Acute stagep valueAfebrile stagep valueSubacute stagep value
boys/girls52/220.015    33/33
Age, months (range)26(3–119)0.316    33 (2–169)
Weight (kg)14.7 (6.5–43)0.416    14.8 (6.8–47)
Days of fever (range)5.5 (2–15)     
CaN (ng/ml)2.97 ± 0.63<0.0012.71 ± 0.57**<0.0012.46 ± 0.49**▲▲<0.0011.46 ± 0.33
NFAT1(pg/ml)305.62 ± 29.29<0.001283.77 ± 24.51**<0.001259.71 ± 24.42**▲▲<0.001218.08 ± 32.10
WBC(× 109/L)14.67 ± 6.13<0.0018.5 ± 3.38**0.3557.53 ± 2.09**<0.0018.9 ± 2.36
NFAT/WBC27.12 ± 21.580.75638.64 ± 15.55**<0.00137.03 ± 11.08**<0.00126.27 ± 8.99
CaN/WBC0.27 ± 0.240.0040.38 ± 0.19**<0.0010.35 ± 0.12*<0.0010.18 ± 0.07
N(×109/L)10.12 ± 5.04<0.0013.76 ± 2.65**0.8212.78 ± 1.34**<0.0013.85 ± 1.82
N(%)66 ± 15<0.00141 ± 16**0.64436 ± 13**0.01242 ± 13
CRP (mg/l)75.26 ± 52.59<0.00113.96 ± 14.83**<0.0013.18 ± 2.83**0.9483.15 ± 3.09
PLT(×109/L)371.23 ± 147.020.013549.30 ± 168.20**<0.001361.31 ± 162.99▲▲0.003320.98 ± 70.44
ESR (mm/h)71.89 ± 33.7588.81 ± 29.18**18.57 ± 15.27**▲▲ 
IL-2(pg/ml)4.15 ± 1.28<0.001    3.05 ± 0.89
IL-4(pg/ml)5.31 ± 5.00<0.001    2.633 ± 0.69
IL-6(pg/ml)97.3 ± 139.7<0.001    11.7 ± 19.87
IL-10(pg/ml)17.76 ± 21.03<0.001    4.86 ± 5.7
  1. All p values are for patients versus healthy control. CaN Calcineurin, NFAT nuclear factor of activated T cells, WBCs white blood cells, N neutrophil, CRP C-reactive protein, PLT platelet, ESR erythrocyte sedimentation rate, IL-2 Interleukin-2; **p < 0.01 compared with acute stage; p < 0.05, ▲▲p < 0.01 compared with afebrile stage