Table 1 Characteristics of the patients with Kawasaki disease and Healthy control
Characteristics | Kawasaki disease | Healthy Control | |||||
|---|---|---|---|---|---|---|---|
Acute stage | p value | Afebrile stage | p value | Subacute stage | p value | ||
boys/girls | 52/22 | 0.015 | 33/33 | ||||
Age, months (range) | 26(3–119) | 0.316 | 33 (2–169) | ||||
Weight (kg) | 14.7 (6.5–43) | 0.416 | 14.8 (6.8–47) | ||||
Days of fever (range) | 5.5 (2–15) | – | |||||
CaN (ng/ml) | 2.97 ± 0.63 | <0.001 | 2.71 ± 0.57** | <0.001 | 2.46 ± 0.49**▲▲ | <0.001 | 1.46 ± 0.33 |
NFAT1(pg/ml) | 305.62 ± 29.29 | <0.001 | 283.77 ± 24.51** | <0.001 | 259.71 ± 24.42**▲▲ | <0.001 | 218.08 ± 32.10 |
WBC(× 109/L) | 14.67 ± 6.13 | <0.001 | 8.5 ± 3.38** | 0.355 | 7.53 ± 2.09** | <0.001 | 8.9 ± 2.36 |
NFAT/WBC | 27.12 ± 21.58 | 0.756 | 38.64 ± 15.55** | <0.001 | 37.03 ± 11.08** | <0.001 | 26.27 ± 8.99 |
CaN/WBC | 0.27 ± 0.24 | 0.004 | 0.38 ± 0.19** | <0.001 | 0.35 ± 0.12* | <0.001 | 0.18 ± 0.07 |
N(×109/L) | 10.12 ± 5.04 | <0.001 | 3.76 ± 2.65** | 0.821 | 2.78 ± 1.34** | <0.001 | 3.85 ± 1.82 |
N(%) | 66 ± 15 | <0.001 | 41 ± 16** | 0.644 | 36 ± 13** | 0.012 | 42 ± 13 |
CRP (mg/l) | 75.26 ± 52.59 | <0.001 | 13.96 ± 14.83** | <0.001 | 3.18 ± 2.83**▲ | 0.948 | 3.15 ± 3.09 |
PLT(×109/L) | 371.23 ± 147.02 | 0.013 | 549.30 ± 168.20** | <0.001 | 361.31 ± 162.99▲▲ | 0.003 | 320.98 ± 70.44 |
ESR (mm/h) | 71.89 ± 33.75 | – | 88.81 ± 29.18** | – | 18.57 ± 15.27**▲▲ | – | |
IL-2(pg/ml) | 4.15 ± 1.28 | <0.001 | 3.05 ± 0.89 | ||||
IL-4(pg/ml) | 5.31 ± 5.00 | <0.001 | 2.633 ± 0.69 | ||||
IL-6(pg/ml) | 97.3 ± 139.7 | <0.001 | 11.7 ± 19.87 | ||||
IL-10(pg/ml) | 17.76 ± 21.03 | <0.001 | 4.86 ± 5.7 | ||||