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Table 1 Clinical and laboratory data in JDM patients and pediatric controls (n = 40)a

From: Assessment of traditional and non-traditional risk factors for premature atherosclerosis in children with juvenile dermatomyositis and pediatric controls

 Total (n = 40)Pediatric controls (n = 20)JDM patients (n = 20)p-value
Age (years)12.4 ± 4.112.7 ± 3.912.1 ± 4.40.651
Female gender28 (70%)14 (70%)14 (70%)> 0.999
Race   0.392
 White, non-Hispanic14 (35%)5 (25%)9 (45%) 
 Black, non-Hispanic8 (20%)4 (20%)4 (20%) 
 Hispanic18 (45%)11 (55%)7 (35%) 
BMI20.9 ± 520.9 ± 4.921 ± 5.10.950
BMI category   > 0.999
 Healthy24 (60%)12 (60%)12 (60%) 
 Overweight/Obese16 (40%)8 (40%)8 (40%) 
Positive cardiac family history23 (58%)12 (60%)11 (58%)0.894
Systolic blood pressure (mmHg)109.8 ± 10.8106.9 ± 10.5112.8 ± 10.50.081
Diastolic blood pressure (mmHg)66 ± 763.7 ± 6.968.4 ± 6.60.035
Total cholesterol (mg/dL)159.1 ± 32.9163.1 ± 29.1154.8 ± 36.70.441
LDL (mg/dL)87.6 ± 25.592.8 ± 23.582.3 ± 27.00.203
HOMA-IRb2.1 [1.4, 3.1]2 [1.7, 2.8]2.1 [1.2, 3.3]0.922
Hemoglobin A1c5.5 ± 0.35.6 ± 0.35.4 ± 0.30.084
Lipoprotein A (nmol/L)c46 [14,87]66 [24,91]16.5 [10, 70]0.055
Apolipoprotein B/A1 ratio0.5 ± 0.10.53 ± 0.10.46 ± 0.10.082
hsCRP (mg/L)0.2 [0.1, 0.7]0.3 [0.2, 0.8]0.2 [0.1, 0.4]0.178
RHI1.57 [1.2,1.9]1.43 [1.2, 1.7]1.72 [1.3, 2.4]0.148
Abnormal RHI < 1.6725 (63%)15 (75%)10 (50%)0.103
Log RHI0.45 ± 0.330.36 ± 0.240.54 ± 0.390.089
  1. a Continuous variables expressed as mean ± standard deviation or median [interquartile range]. Categorical variables expressed as frequency (percentages)
  2. b Homeostatic Model Assessment for Insulin Resistance (HOMA-IR): HOMA-IR = fasting insulin x fasting glucose / 22.5 [43]
  3. c Only evaluated in 31 participants (17 pediatric controls and 14 JDM patients)