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Fig. 1 | Pediatric Rheumatology

Fig. 1

From: The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis

Fig. 1

a and b show serum levels of S100A8/9 (a) and S100A12 (b) across diagnoses. Values represent median and IQR (error bars). Comparison between diagnoses are done by Kruskal-Wallis test. c and d show receiver operating charachteristic (ROC) curves for S100A8/9 (c) and S100A12 (d) in differentiating systemic juvenile idiopathic arthritis (sJIA) vs. Other autoinflammatory syndromes designated as autoinflammatory disease + systemic undifferentiated recurring fever syndromes (AID + SURFS). The area under the curve (AUC) for both S100A8/9 and S100A12 is 0.9. Sensitivities and specificties for the cut-off values are outlined. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001

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