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Table 3 Univariate logistic regression of refractory and non-refractory groups of anti-NXP2 autoantibody positive JDM

From: Clinical characteristics and poor predictors of anti-NXP2 antibody-associated Chinese JDM children

  

Outcome ratio (%)

N

β

OR

95%CI

P-values

Gender

male

33.33

26

0.5534

1.739

0.257 ~ 14.451

0.8037

female

47.06

BMI (kg/m2)

> = 15

33.33

25

1.5396

4.663

0.558 ~ 62.967

0.2032

< 15

71.43

Muscle strength

> 3

0

26

2.6654

14.373

2.461~ > 999.999

0.0041*

<=3

61.11

Edema

No

11.76

25

3.926

50.705

8.086~ > 999.999

<.0001*

Yes

100

Skin ulcer

No

12.5

26

3.8559

47.27

3.869~ > 999.999

0.0003*

Yes

90

Dysphagia/hoarseness/soft voice

No

9.09

26

2.8634

17.521

1.691 ~ 952.094

0.0089*

Yes

66.67

Symptom

No

10

26

2.5977

13.433

1.308 ~ 721.398

0.0219*

Yes

62.5

ILD

No

27.78

25

1.7855

5.963

0.698 ~ 82.561

0.1237

Yes

71.43

ANA (+)

No

21.43

26

1.9024

6.702

0.987 ~ 61.614

0.0521

Yes

66.67

Anti-Ro-52 (+)

No

31.58

26

1.6178

5.042

0.609 ~ 67.675

0.1696

Yes

71.43

CD4/CD8 ratio

> = 1.4

18.75

24

2.4221

11.269

1.26 ~ 171.48

0.0255*

< 1.4

75

Ferritin (ng/ml)

<=200

16.67

24

2.1876

8.914

1.115 ~ 123.379

0.0361*

> 200

66.67

  1. Outcome ratio the ratio of outcomes in different condition, Symptom at least one of edema, skin ulcer or Dysphagia/Hoarseness/Lower voice, BMI body mass index, ILD interstitial lung disease, ANA antinuclear antibody; *: significantly statistic difference, P < 0.05