Skip to main content
Fig. 4 | Pediatric Rheumatology

Fig. 4

From: Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation

Fig. 4

Using ELISA to study the effects of exogenous BMP4 on protein expression of BMP antagonists in cell media supernatants over 24 h. JFLS, in the presence of BMP4, significantly decrease expression of noggin and follistatin (a and b) (p < 0.05) while gremlin and chordin remained unchanged in FLS exposed to exogenous BMP4 (c and d)

Back to article page

Pediatric Rheumatology

ISSN: 1546-0096