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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation

Fig. 2

Protein expression of BMP antagonists: chordin, noggin, follistatin, and gremlin. JFLS significantly overexpress chordin (a) and noggin (b) when compared to Ch (p < 0.05, t-test) as determined by ELISA on cell media supernatants. CFLS exhibit a significant decrease in follistatin when compared to untreated Ch (c) while gremlin remained unchanged in FLS when compared to Ch (d)

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Pediatric Rheumatology

ISSN: 1546-0096