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Table 1 Baseline demographic and clinical characteristics before and after implementation of standardized outcome monitoring and CDS for polyarticular JIA

From: Determinants of disease activity change over time in Enthesitis related arthritis: effect of structured outcome monitoring and clinical decision support

 

All N = 152

Pre-intervention N = 54

Phase I N = 98

p-value

Incident diagnosis, n (%)

46 (30)

15 (28)

31 (32)

0.62

Age, median (IQR)

14.9 (12.2–17.4)

15.5 (12.1–16.8)

14.8 (12.2–17.5)

0.79

Male, n (%)

98 (64)

35 (65)

63 (64)

0.95

Race (Non-white) n (%)

23 (15)

7 (13)

16 (16)

0.58

Hispanic Ethnicity, n (%)

9 (5)

4 (7)

5 (5)

0.56

Public insurance, n (%)

67 (44)

17 (31)

50 (51)

0.02

ILAR Criteria for ERA

•Presence of arthritis, n (%)

131 (86)

47 (87)

84 (86)

0.82

•Presence of enthesitis, n (%)

129 (85)

48 (89)

81 (83)

0.31

•Arthritis in a male > 6 year, n (%)

68 (45)

26 (48)

42,843)

0.53

•SIJ tenderness, n (%)

64 (42)

24 (44)

40 (41)

0.67

•Acute anterior uveitis, n (%)

14 (9)

4 (7)

10 (10)

0.57

•Family history of HLA-B27 related disease, n (%)

12 (8)

5 (9)

7 (7)

0.64

Baseline paina, median (IQR)

1.9 (0.1–4.9)

1.0 (0.0–3.0)

2.1 (0.4–5.3)

0.02

Baseline cJADASb, median (IQR)

3.0 (0.9–8.0)

3.0 (1.0–6.0)

4.5 (0.6–8.3)

0.09

•Active Joint Countc

0.0 (0.0–1.0)

0.0 (0.0–1.0)

0.0 (0.0–1.0)

0.25

•Physician’s global assessmentd

1.0 (0.0–3.0)

0.0 (0.0–2.0)

1.0 (0.0–3.0)

0.07

•Patient/parent global assessmente

1.8 (0.3–3.9)

1.5 (0.0–3.0)

1.9 (0.4–4.1)

0.27

Baseline tender entheses countf, median (IQR)

0.0 (0.0–2.0)

0.0 (0.0–2.0)

0.0 (0.0–1.0)

0.11

HLA – B27 positiveg, n (%)

62 (42)

19 (36)

43 (46)

0.24

Polyarticular disease, n (%)

42 (28)

16 (31)

26 (27)

0.58

Sacroilitis confirmed by MRI (ever), n (%)

42 (28)

15 (28)

27 (28)

0.97

Biologic use (ever)

101 (66)

35 (65)

66 (67)

0.75

DMARD use (ever)

58 (38)

20 (37)

38 (39)

0.83

  1. aPain visual analog scale score (range 0,10); bcJADAS = three-variable clinical Juvenile Arthritis Disease Activity Score (range 0,30); cActive joint count (range 0,10); dPhysician global assessment of disease activity visual analog scale (range 0,10); ePatient/parent global assessment of disease activity visual analog scale (range 0,10); f (range 0,14) gB27 status missing for 4 subjects
  2. Abbreviations: CDS Clinical Decision Support, IQR interquartile range, ILAR International League of Associations for Rheumatology, ERA Enthesitis Related Arthritis, SIJ Sacroiliac Joints, HLA Human Leukocyte Antigen, MRI Magnetic Resonance Imaging, DMARD Disease modifying Anti Rheumatic Drug