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Table 1 Clinical symptoms and ESSDAI items of sicca-positive and -negative patients at baseline

From: Utility of the EULAR Sjögren syndrome disease activity index in Japanese children: a retrospective multicenter cohort study

 

Clinical symptoms at first visit

Initial ESSDAI

All patients

(n = 31)

Sicca (+)

(n = 9)

Sicca (−)

(n = 22)

(12 domains)

Glandular involvement

15 (48.4%)

 

 Sicca symptoms

9 (29.0%)

9

0

 

 Recurrent parotitis (glandular)

9 (29.0%)

3

6

10 (32.3%)

Extraglandular symptoms

29 (93.5%)

9

20

 

 Constitutional (fever)

19 (61.3%)

5

14

18 (58.1%)

 Lymphadenopathy

7 (22.6%)

1

6

9 (29.0%)

 Arthritis/arthralgia

14 (45.2%)

4

10

9 (29.0%)

 Cutaneous (annular erythema)

7 (22.6%)

3

4

9 (29.0%)

 Cutaneous (purpura)

6 (19.4%)

4

2

 Peripheral neurologic symptoms

1 (3.2%)

1

0

2 (6.5%)

 Central nervous system symptoms

1 (3.2%)

1

0

3 (9.7%)

 Raynaud’s symptoms

5 (16.1%)

2

3

 

 General fatigue

13 (41.9%)

3

10

 

Symptoms/data of other ESSDAI domains

 Pulmonary

0 (0%)

0

0

0 (0%)

 Renal

0 (0%)

0

0

1 (3.2%)

 Muscle

0 (0%)

0

0

0 (0%)

 Hematological

   

3 (9.7%)

 Biological

   

18 (58.1%)

  1. The last column, Initial ESSDAI, lists number (%) of patients who were positive for each disease feature on the Initial ESSDAI within 6 months of the first visit
  2. Abbreviations: ESSDAI EULAR Sjögren Syndrome Disease Activity Index, EULAR European League Against Rheumatism