Skip to main content

Table 1 Clinical symptoms and ESSDAI items of sicca-positive and -negative patients at baseline

From: Utility of the EULAR Sjögren syndrome disease activity index in Japanese children: a retrospective multicenter cohort study

  Clinical symptoms at first visit Initial ESSDAI
All patients
(n = 31)
Sicca (+)
(n = 9)
Sicca (−)
(n = 22)
(12 domains)
Glandular involvement 15 (48.4%)  
 Sicca symptoms 9 (29.0%) 9 0  
 Recurrent parotitis (glandular) 9 (29.0%) 3 6 10 (32.3%)
Extraglandular symptoms 29 (93.5%) 9 20  
 Constitutional (fever) 19 (61.3%) 5 14 18 (58.1%)
 Lymphadenopathy 7 (22.6%) 1 6 9 (29.0%)
 Arthritis/arthralgia 14 (45.2%) 4 10 9 (29.0%)
 Cutaneous (annular erythema) 7 (22.6%) 3 4 9 (29.0%)
 Cutaneous (purpura) 6 (19.4%) 4 2
 Peripheral neurologic symptoms 1 (3.2%) 1 0 2 (6.5%)
 Central nervous system symptoms 1 (3.2%) 1 0 3 (9.7%)
 Raynaud’s symptoms 5 (16.1%) 2 3  
 General fatigue 13 (41.9%) 3 10  
Symptoms/data of other ESSDAI domains
 Pulmonary 0 (0%) 0 0 0 (0%)
 Renal 0 (0%) 0 0 1 (3.2%)
 Muscle 0 (0%) 0 0 0 (0%)
 Hematological     3 (9.7%)
 Biological     18 (58.1%)
  1. The last column, Initial ESSDAI, lists number (%) of patients who were positive for each disease feature on the Initial ESSDAI within 6 months of the first visit
  2. Abbreviations: ESSDAI EULAR Sjögren Syndrome Disease Activity Index, EULAR European League Against Rheumatism