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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: A familial case of Kikuchi-Fujimoto disease in dizygotic twins

Fig. 2

Histopathology slides taken from a lymph node biopsy of Twin 2 with immunohistochemical staining for various cell surface markers. a – Positive staining for MUM1 (general lymphocyte activation marker). b – Positive staining for CD4 (T-cell marker). c – Positive staining for CD68 (histiocyte marker). d – Negative staining for CD20 (B-cell marker). This shows the abnormal population of epithelioid cells which are positive for T-cell and hystiocyte markers and negative for B-cell markers and thus are the blastic T-cells that proliferate in Kikuchi-Fujimoto disease

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