Fig. 1

Histopathology slides taken from a lymph node biopsy of Twin 2. Stained with Haematoxylin and Eosin with magnification as noted in the images. a – Loss of the normal follicular architecture of the lymph node with an area of abnormal cellularity in the subcapsular area. b – Abrupt coagulative necrosis with no neutrophils (“sterile” necrosis). c – Epithelioid cells with abnormal morphology which are the cells of origin for the coagulative necrosis