Table 1 The comparison of demographic, clinical characteristic and laboratory results of Kawasaki disease between the two groups

 Patients, n

80

512

–

 Sex, male, n(%)

46(57.5)

296(57.8)

0.526

 Age, months

33.0 ± 26.8

30.4 ± 23.4

0.437

 Fever duration on admission, days

5.5 ± 3.0

5.5 ± 2.8

0.893

 Incomplete Kawasaki disease, n(%)

34(42.5)

192(37.5)

0.390

 Kawasaki disease shock syndrome, n(%)

10(12.5)

1(0.2)

<0.001^*

 Fever, n(%)

80(100.0)

512(100.0)

–

 Rash, n(%)

60(75.0)

395(77.1)

0.670

 Edema & erythema of the extremities, n(%)

46(57.5)

297(58.0)

0.863

 Bilateral bulbar conjunctival injection, n(%)

70(87.5)

464(90.6)

0.480

 Erythema of oral and pharyngeal mucosa, n(%)

72(90.0)

470(91.8)

0.524

 Cervical lymphadenopathy, n(%)

38(47.5)

220(43.1)

0.470

 The duration of antibiotic, days

6.4 ± 2.5

4.8 ± 2.2

<0.001^*

 Fever duration before IVIG, days

6.4 ± 4.0

6.3 ± 3.0

0.782

 The delayed treatment of initial IVIG (>10 days)

4(5.0)

21(4.1)

0.762

 Failure to respond to initial IVIG therapy, n(%)

22(27.5)

70(13.7)

0.003^*

  Patients from Cardiology Department, n(%)

9 (11.3)

62(12.1)

0.837

  Patients from non-Cardiology Department, n(%)

13 (16.3)

8(1.6)

<0.001^*

 Intravenous and/or Oral steroid treatment, n(%)

13(16.3)

38(7.4)

0.016^*

 Coronary artery lesions, n(%)

12(15.0)

50(9.8)

0.220

  Dilatation, n(%)

11(13.8)

45(8.8)

0.180

  Aneurysms, n(%)

1(1.3)

5(1.0)

0.821

 Valve regurgitation, n(%)

8(10.0)

32(6.3)

0.229

 Cardiac enlargement, n(%)

10(12.5)

37(7.2)

0.118

 Pericardial effusion, n(%)

4(5.0)

12(2.3)

0.253

 White blood cell count, × 10⁹/L

15.5 ± 5.8

14.3 ± 5.4

0.042^*

 Neutrophil rate, %

70.3 ± 17.0

66.1 ± 14.7

0.014^*

 Lymphocyte rate, %

19.6 ± 12.3

25.1 ± 12.9

<0.001^*

 C-reactive proteins, mg/L

96.0 ± 53.1

79.3 ± 47.8

0.003^*

 Erythrocyte sediment rate, mm/h

69.4 ± 34.1

65.1 ± 29.1

0.326

 Platelet, ×10⁹/L

325.0 ± 117.0

343.9 ± 115.0

0.164

 Hemoglobin, g/L

104.0 ± 13.3

108.4 ± 10.9

0.001^*

 Alanine transaminase, U/L

75.2 ± 83.9

67.8 ± 84.4

0.516

 Aspartate transaminase, U/L

58.9 ± 88.3

49.5 ± 57.0

0.233

 Albumin, g/L

34.4 ± 7.0

37.7 ± 5.0

<0.001^*

 Total bilirubin, umol/L

10.3 ± 15.3

7.7 ± 7.9

0.026^*

 Cr, umol/L

33.5 ± 14.6

28.2 ± 13.8

0.003^*

 Serum sodium, mmol/L

135.3 ± 4.8

136.3 ± 7.1

0.098