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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: Adenosine deaminase 2 activity negatively correlates with age during childhood

Fig. 2

Plasma ADA2 enzyme activity and concentration in a healthy pediatric cohort. Plasma samples from otherwise healthy children and adolescents (x-axis, unless otherwise noted) aged 0–2 yrs (n = 16), 3–5 yrs (n = 19), 6–8 yrs (n = 18), 9–11 yrs (n = 16), 12–14 yrs (n = 13), 15–18 yrs (n = 12) and healthy adults (> 18 yrs, n = 5) were analyzed. a–b ADA2 enzyme activity (y-axis: ADA2 activity (U/L)). c–d ADA2 concentration (y-axis: ADA2 concentration (μg/mL)). e–f ADA2 activity normalized to ADA2 concentration (y-axis: ADA2 activity (mU/mg). Trend lines show linear regression of data. Outliers are denoted by open shapes and were excluded from statistical analyses. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001

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