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Table 2 The Allelic Frequency of MEFV mutations or variants in the current study

From: The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis

Mutation or variantssJIA patients(n = 57)Controls(n = 2573)OR95%CI
mutated allelewide type allelemutated allelewide type allele
E148Q2688132638200.850.55–1.32
L110P411033748090.520.19–1.42
R202Q610819149551.440.63–3.32
G304R11137050760.640.09–4.66
P369S510935647900.620.25–1.52
R408Q411024948970.720.26–1.96
c.1759 + 8c > t810652146250.670.32–1.38
  1. R202Q, G304R, and c.1759 + 8c > t were regarded as benign or likely benign variants while other variants in the table were categorized as variants of uncertain significance according to the new workflow of International Study Group for Systemic Autoinflammatory Diseases
  2. Abbreviation: sJIA systemic juvenile idiopathic arthritis