Fig. 2From: Familial chilblain lupus due to a novel mutation in TREX1 associated with Aicardi–Goutie’res syndromeChilblain lesions on skin of the patients. Skin features observed in the affected families(II-5, III-6, III-7, IV-1). Previous ulcerations have led to a loss of the distal interphalangeal joints in patient II-5Back to article page