Table 4 Demographics and Treatment
Subject | Sex | Age (yrs) | Disease duration at first visit (m) | Year of first visit | Follow up duration (m) | Disease status at last visit | Medication at last visit | Summary of disease course |
|---|---|---|---|---|---|---|---|---|
1 | M | 11 | 24 | 2017 | 12 | inactive | yes | Treated with 11 weeks of antibiotics and partially responded. Then treated with monthly pamidronate for 4 doses with partial response. Then switched to anti TNF therapy with full response. |
2 | F | 15 | 11 | 2016 | 16 | inactive | yes | Treated with 4 weeks of antibiotics and partially responded. Then treated with NSAIDS for 24 months with full response. |
3 | M | 6 | 18 | 2012 | 58 | inactive | yes | Treated with unknown duration of antibiotics with no response. Then treated with NSAIDS for 5 years with no response. MTX was also tried for 5 years and showed partial response. Responded partially from 3 days of steroid. Then switched to biologic for 3.5 years and showed partial response. Lastly switched to pamidronate with full response. |
5 | M | 11 | 23 | 2012 | 8 | inactive | yes | Treated with 12 weeks of antibiotics with no response. Then treated with NSAIDS for 10 months with full response. |
6 | F | 12 | 6 | 2015 | 1 | active | no | Treated with antibiotics with no response. |
9 | M | 6 | 6 | 2013 | 16 | active | yes | Treated with NSAIDS for 14 months with no response. Then switched to MTX/SSZ. |
10 | F | 5 | 7 | 2016 | 16 | inactive | yes | Treated with 1 month of antibiotics with no response. Then treated with 16 months of NSAIDS. Also received 12 months of MTX/SSZ with no response. Received monthly pamidronate for 6 doses with partial response. Then switched to anti TNF therapy with full response. |
11 | M | 15 | 19 | 2012 | 29 | inactive | no | Treated with 4 years of NSAIDS and partially responded. Received steroids with partial response. Then switched to MTX/SSZ with full response. |
12 | M | 12 | 13 | 2012 | 23 | inactive | yes | Received anti TNF therapy for 3.5 years with partial response. |
13 | F | 11 | 4 | 2017 | 2 | active | yes | Treated with 2 weeks of antibiotics with no response. Then treated with MTX/SSZ for 1 month and NSAIDS for 2 months with partial response. |
15 | F | 3 | 6 | 2016 | 19 | inactive | no | Treated with 11 days of antibiotics. Then switched to 2 months of steroids and 5 months of MTX/SSZ with partial response. Finally treated with monthly pamidronate for 11 doses with full response. |
16 | M | 12 | 1 | 2015 | 15 | active | no | Treated with 2 weeks of antibiotics. Then switched to 15 months of NSAIDs with partial response. |
18 | M | 11 | 12 | 2003 | 84 | inactive | no | Treated with >2 weeks of antibiotics with no response. Then treated with 70 months of NSAIDS with partial response. Received 4.5 months of steroids with partial response. |
20 | M | 11 | 10 | 2008 | 55 | active | yes | Treated with 2 months of antibiotics with no response. Treated with NSAIDS for 66 months with partial response. Then treated with 5 months of MTX/SSZ and 4 months of steroids with partial response. |
21 | F | 14 | 36 | 2009 | 16 | active | yes | Treated with 9 months of antibiotics and partially responded. Then treated with 19 months of NSAIDs with no response. Then switched to MTX/SSZ for 20 months with partial response. Also received 17 months of steroids with partial response. |
22 | M | 12 | 0 | 2014 | 47 | inactive | no | Treated with 6 weeks of antibiotics with no response. Received 2 years of NSAIDs with no response. Then treated with 28 months of MTX/SSZ with partial response. Finally received monthly pamidronate for 4 doses with with full response. |
23 | F | 8 | 13 | 2016 | 2 | active | yes | Treated with 3 weeks of antibiotics with no response. Then treated with 3 months of NSAIDs with partial response. |
26 | F | 9 | 31 | 2016 | 14 | inactive | yes | Treated with 2 months of antibiotics with no response. Then received 20 months of NSAIDs and intermittent steroids with partial response. Then switched to anti TNF therapy with full response. |
27 | M | 11 | 42 | 2005 | 49 | inactive | no | Treated with 3 weeks of antibiotics with no response. Then treated with 38 months of NSAIDs and 10 weeks of steroids with partial response. |
29 | M | 7 | 36 | 2016 | 18 | inactive | yes | Treated with 14 months of NSAIDs with no response. Then treated with 17 months of MTX/SSZ and 8 weeks of steroids with partial response. Switched to monthly pamidronate for 11 doses with full response. |
30 | M | 7 | 4 | 2005 | 97 | active | yes | Treated with 21 days of antibiotics with no response. Then treated with 8 years of NSAIDs with partial response. |
31 | M | 11 | several years | 2008 | 90 | active | yes | Treated with 96 months of NSAIDs and 55 days of steroids and partially responded. |