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Table 4 Demographics and Treatment

From: Pediatric chronic nonbacterial osteomyelitis of the mandible: Seattle Children’s hospital 22-patient experience

SubjectSexAge (yrs)Disease duration at first visit (m)Year of first visitFollow up duration (m)Disease status at last visitMedication at last visitSummary of disease course
1M1124201712inactiveyesTreated with 11 weeks of antibiotics and partially responded. Then treated with monthly pamidronate for 4 doses with partial response. Then switched to anti TNF therapy with full response.
2F1511201616inactiveyesTreated with 4 weeks of antibiotics and partially responded. Then treated with NSAIDS for 24 months with full response.
3M618201258inactiveyesTreated with unknown duration of antibiotics with no response. Then treated with NSAIDS for 5 years with no response. MTX was also tried for 5 years and showed partial response. Responded partially from 3 days of steroid. Then switched to biologic for 3.5 years and showed partial response. Lastly switched to pamidronate with full response.
5M112320128inactiveyesTreated with 12 weeks of antibiotics with no response. Then treated with NSAIDS for 10 months with full response.
6F12620151activenoTreated with antibiotics with no response.
9M66201316activeyesTreated with NSAIDS for 14 months with no response. Then switched to MTX/SSZ.
10F57201616inactiveyesTreated with 1 month of antibiotics with no response. Then treated with 16 months of NSAIDS. Also received 12 months of MTX/SSZ with no response. Received monthly pamidronate for 6 doses with partial response. Then switched to anti TNF therapy with full response.
11M1519201229inactivenoTreated with 4 years of NSAIDS and partially responded. Received steroids with partial response. Then switched to MTX/SSZ with full response.
12M1213201223inactiveyesReceived anti TNF therapy for 3.5 years with partial response.
13F11420172activeyesTreated with 2 weeks of antibiotics with no response. Then treated with MTX/SSZ for 1 month and NSAIDS for 2 months with partial response.
15F36201619inactivenoTreated with 11 days of antibiotics. Then switched to 2 months of steroids and 5 months of MTX/SSZ with partial response. Finally treated with monthly pamidronate for 11 doses with full response.
16M121201515activenoTreated with 2 weeks of antibiotics. Then switched to 15 months of NSAIDs with partial response.
18M1112200384inactivenoTreated with >2 weeks of antibiotics with no response. Then treated with 70 months of NSAIDS with partial response. Received 4.5 months of steroids with partial response.
20M1110200855activeyesTreated with 2 months of antibiotics with no response. Treated with NSAIDS for 66 months with partial response. Then treated with 5 months of MTX/SSZ and 4 months of steroids with partial response.
21F1436200916activeyesTreated with 9 months of antibiotics and partially responded. Then treated with 19 months of NSAIDs with no response. Then switched to MTX/SSZ for 20 months with partial response. Also received 17 months of steroids with partial response.
22M120201447inactivenoTreated with 6 weeks of antibiotics with no response. Received 2 years of NSAIDs with no response. Then treated with 28 months of MTX/SSZ with partial response. Finally received monthly pamidronate for 4 doses with with full response.
23F81320162activeyesTreated with 3 weeks of antibiotics with no response. Then treated with 3 months of NSAIDs with partial response.
26F931201614inactiveyesTreated with 2 months of antibiotics with no response. Then received 20 months of NSAIDs and intermittent steroids with partial response. Then switched to anti TNF therapy with full response.
27M1142200549inactivenoTreated with 3 weeks of antibiotics with no response. Then treated with 38 months of NSAIDs and 10 weeks of steroids with partial response.
29M736201618inactiveyesTreated with 14 months of NSAIDs with no response. Then treated with 17 months of MTX/SSZ and 8 weeks of steroids with partial response. Switched to monthly pamidronate for 11 doses with full response.
30M74200597activeyesTreated with 21 days of antibiotics with no response. Then treated with 8 years of NSAIDs with partial response.
31M11several years200890activeyesTreated with 96 months of NSAIDs and 55 days of steroids and partially responded.
  1. NSAID nonsteroidal anti inflammatory durg, MTX methotrexate, SSZ sulfasalazine