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Table 1 Patient characteristics and summary of clinical assessments at baseline (B) and follow-up (F)

From: Can quantitative MRI be used in the clinical setting to quantify the impact of intra-articular glucocorticoid injection on synovial disease activity in juvenile idiopathic arthritis?

Subject

Age

Gender

Disease duration (months)

ILAR Subtype & Systemic Medication

Active joint count

Clinician assessed disease activity in injected knee (Y/N)

JADAS10

cJADAS10

ESR

CHAQ

Pain global score (cm)

     

B

F

B

F

B

F

B

F

B

F

B

F

B

F

1

12.3

F

0

psoriatic m

1lk

1lk

Y

Y

n/a

5.5

9.3

5.5

n/a

10

1.4

n/a

6.1

4.0

2

7.7

F

27

per oligo m

2rk,ra

–

Y

–

7.0

–

7.0

–

20

–

0.3

–

3.2

–

3

16.0

F

8

per oligo z

2lk,rk

0

Y

N

8.4

0.0

7.8

0.0

26

16

0.5

0

3.3

0.0

4

11.6

M

140

per oligo

1rk

1rk

Y

Y

4.2

2.0

4.2

2.0

5

2

1.0

0

3.6

0.0

5

13.4

M

53

ext oligo

1lk

1rk

Y

N

7.1

n/a

7.1

3.0

2

n/a

0.0

0

3.0

1.5

6

16.2

F

6

RF+ poly m,d

2lk,rk

0

Y

N

7.2

0.0

7.2

0.0

5

5

1.0

0.3

2.9

0.9

7

13.6

F

54

per oligo d

2lk,rk

0

Y

N

12.4

0.0

11.0

0.0

34

15

0.5

0

6.3

0.0

8

8.1

M

0

per oligo

2lk,rk

2rk,ra

Y

Y

18.8

8.9

15.6

8.9

52

9

1.9

1.9

10.0

6.8

9

13.4

M

74

ext oligo d

2lk,rk

0

Y

N

10.8

1.2

10.0

1.2

28

15

1.3

n/a

6.5

6.1

10

15.3

F

92

RF- poly

1rk

0

Y

N

9.2

n/a

9.2

4.2

16

n/a

1.3

n/a

7.1

3.4

11

14.3

M

14

per oligo

1rk

0

Y

N

2.0

0.0

2.0

0.0

2

5

0.0

n/a

0.0

0.0

Median

13.4

 

27

 

1.5

0.0†

  

–

–

8.5

1.6*

–

–

–

–

4.9

1.2$

IQR

2.8

 

57

 

1.0

1.0

  

–

–

2.7

3.9

–

–

–

–

3.4

3.9

  1. Medians and interquartile ranges (IQR) comparing baseline and follow-up exclude subject 2 who was lost to follow-up. Where measurements are not available for other individuals, medians have not been provided. †p < 0.03, * p = 0.005, $ p = 0.008 at follow-up compared to baseline. Key: per/ext. oligo = persistent/extended oligoarticular, RF+/RF- poly = rheumatoid factor positive/negative polyarticular, JADAS10 = juvenile arthritis disease activity score (10 joints), cJADAS10 = clinical juvenile arthritis disease activity score (10 joints), ESR = erythrocyte sedimentation rate, CHAQ = child health assessment questionnaire, n/a = not available. For active joint counts, superscripts specify joints (lk = left knee, rk = right knee, ra = right ankle). The imaged knee is underlined. Systemic medication: m = methotrexate, z = azathioprine, d = adalimumab