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Fig. 1 | Pediatric Rheumatology

Fig. 1

From: Can quantitative MRI be used in the clinical setting to quantify the impact of intra-articular glucocorticoid injection on synovial disease activity in juvenile idiopathic arthritis?

Fig. 1

Procedure for calculating the synovial volume, shown on one slice of the imaged knee volume. The acquired data are (a) the multi-slice T1-weighted FS TSE pre-contrast and (b) post-contrast showing synovial hypertrophy. (c) These image stacks are subtracted to produce a stack of difference images which highlight the signal change caused by contrast uptake compared to other tissues; (d) thresholding these values helps to segment the enhancing synovium from structures with low uptake, though blood vessels remain visible. The magic wand tool of ImageJ is used to select the enhancing synovium; the volume is calculated by summing across the image stack. FS TSE, fat saturated turbo spin echo

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Pediatric Rheumatology

ISSN: 1546-0096