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Table 3 Laboratory tests results collected at diagnosis in ALL and JIA patients

From: Persistent osteoarticular pain in children: early clinical and laboratory findings suggestive of acute lymphoblastic leukemia (a multicenter case-control study of 147 patients)

 ALLJIAp*
(median [interquartile range])(median [interquartile range])
Blood count
 WBC count, 109/L5.3 [3.0–9.5]8.3 [6.6–10.1]< 0.001
  Neutrophils, 109/L0.8 [0.5–1.9]4.0 [3.0–5.7]< 0.001
  Eosinophils, 109/L0.03 [0–0.08]0.02 [0.14–0.33]< 0.001
  Basophils, 109/L0 [0–0]0.03 [0.02–0.05]< 0.001
  Lymphocytes, 109/L2.2 [1.8–3.4]3.0 [2.2–3.8]0.02
  Monocytes, 109/L0.1 [0.05–0.3]0.6 [0.5–0.8]< 0.001
 Hgb, g/dL8.8 [7.5–10.6]11.9 [11.1–12.6]< 0.001
 HCT, %26.0 [22.5–30.1]35.7 [33.7–37.6]< 0.001
 MCV, fL83 [78–86]80 [76–83]0.01
 MCHC, g/dL34 [33–34]34 [33–34]0.64
 Platelets, 109/L121 [71–213]357 [295–430]< 0.001
Inflammatory parameters
 1st hr. ESR, mm75 [36–106]18 [7–55]< 0.001
 CRP, mg/L32 [12–77]3 [0–24]< 0.001
  1. * Univariate analysis with Wilcoxon test
  2. ALL Acute lymphoblastic leukemia, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, HCT Hematocrit, Hgb Hemoglobin, JIA Juvenile idiopathic arthritis, MCHC Mean corpuscular hemoglobin concentration, MCV Mean corpuscular volume, WBC White blood cells