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Table 3 Laboratory tests results collected at diagnosis in ALL and JIA patients

From: Persistent osteoarticular pain in children: early clinical and laboratory findings suggestive of acute lymphoblastic leukemia (a multicenter case-control study of 147 patients)

 

ALL

JIA

p*

(median [interquartile range])

(median [interquartile range])

Blood count

 WBC count, 109/L

5.3 [3.0–9.5]

8.3 [6.6–10.1]

< 0.001

  Neutrophils, 109/L

0.8 [0.5–1.9]

4.0 [3.0–5.7]

< 0.001

  Eosinophils, 109/L

0.03 [0–0.08]

0.02 [0.14–0.33]

< 0.001

  Basophils, 109/L

0 [0–0]

0.03 [0.02–0.05]

< 0.001

  Lymphocytes, 109/L

2.2 [1.8–3.4]

3.0 [2.2–3.8]

0.02

  Monocytes, 109/L

0.1 [0.05–0.3]

0.6 [0.5–0.8]

< 0.001

 Hgb, g/dL

8.8 [7.5–10.6]

11.9 [11.1–12.6]

< 0.001

 HCT, %

26.0 [22.5–30.1]

35.7 [33.7–37.6]

< 0.001

 MCV, fL

83 [78–86]

80 [76–83]

0.01

 MCHC, g/dL

34 [33–34]

34 [33–34]

0.64

 Platelets, 109/L

121 [71–213]

357 [295–430]

< 0.001

Inflammatory parameters

 1st hr. ESR, mm

75 [36–106]

18 [7–55]

< 0.001

 CRP, mg/L

32 [12–77]

3 [0–24]

< 0.001

  1. * Univariate analysis with Wilcoxon test
  2. ALL Acute lymphoblastic leukemia, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, HCT Hematocrit, Hgb Hemoglobin, JIA Juvenile idiopathic arthritis, MCHC Mean corpuscular hemoglobin concentration, MCV Mean corpuscular volume, WBC White blood cells
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Pediatric Rheumatology

ISSN: 1546-0096