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Table 2 Laboratory tests results collected before the diagnosis in ALL and JIA patients

From: Persistent osteoarticular pain in children: early clinical and laboratory findings suggestive of acute lymphoblastic leukemia (a multicenter case-control study of 147 patients)

 ALLJIAp*
Blood count(median [interquartile range])(median [interquartile range]) 
 WBC count, 109/L5.1 [4.2–6.5]8.4 [7.0–10.3]< 0.001
  Neutrophils, 109/L1.6 [0.8–2.9]4.6 [3.3–5.4]< 0.001
  Eosinophils, 109/L0.02 [0–0.06]0.2 [0.1–0.3]< 0.001
  Basophils, 109/L0.003 [0–0.03]0.03 [0.02–0.05]< 0.001
  Lymphocytes, 109/L2.6 [1.8–4.2]2.9 [2.3–3.6]0.56
  Monocytes, 109/L0.2 [0.1–0.4]0.6 [0.5–0.8]< 0.001
 Hgb, g/dL10.6 [9.2–12.1]11.9 [11,3-12,9]0,001
 HCT, %31.8 [27.0–35.5]35.9 [33.3–38.6]< 0.001
 MCV, fL83 [78–86]80 [76–83]0.009
 MCHC, g/dL34 [33–34]34 [33–34]0.84
 Platelets, 109/L218 [158–310]377 [298–439]< 0.001
Inflammatory parameters
 1st hr. ESR, mm56 [35–98]25 [12–48]< 0.001
 CRP, mg/L46 [9–80]8 [2–26]< 0.001
  1. * Univariate analysis with Wilcoxon test
  2. ALL Acute lymphoblastic leukemia, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, HCT Hematocrit, Hgb Hemoglobin, JIA Juvenile idiopathic arthritis, MCHC Mean corpuscular hemoglobin concentration, MCV Mean corpuscular volume, WBC White blood cells