|
Patient median
|
Patient range
|
Normal range
|
---|
A. Complete Blood Cell count (CBC) and liver function values
|
Hb (g/L)
|
114
|
96–126
|
125–165
|
WBC (× 109/L)
|
3
|
1.7–10.9
|
3.9–10.2
|
Platelets (× 109/L)
|
172
|
151–231
|
180–440
|
ALT (U/L)
|
83
|
25–650
|
0–50
|
AST (U/L)
|
97.5
|
66–178
|
0–36
|
LDH (U/L)
|
1151
|
133–1754
|
120–300
|
B. Inflammatory markers
|
CRP (mg/L)
|
5
|
0–45
|
0–5
|
ESR (mm)
|
14
|
4–42
|
0–15
|
Ferritin (ug/L)
|
70
|
29–465
|
31–177
|
SAA (ng/mL)
|
11,765
|
1752 – 193,855
|
1000–5000
|
- aMedian and range calculated from test results obtained approximately three times a year over 10 years (age 5–14 yrs). Normal ranges are age-specific values from the BC Children’s Hospital Clinical Laboratory. Changes in parameters did not correlate with alterations in clinical state and neither correlated with treatment modalities, except for a decrease in SAA upon treatment with canakinumab (Fig. 1)