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Table 2 (abstract A41). Associations between pain amplification and demographic and neuropsychiatric disease characteristics in patients with PANS

From: Proceedings of the 2019 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Annual Scientific Meeting

Variable Pain amplification No pain amplification p-valuea
Male, N (%) 30 / 47 (64%) 40 / 62 (65%) 1.0
Age (years) at PANS onset, Mean (standard deviation) 8.5 (3.4) 8.7 (3.6) 0.8
Years between onset and 1st clinic visit, Median (interquartile range) 1.6 (0.4 to 3.6) 0.8 (0.2 to 2.3) 0.3
Peak myofascial tender points, Median (interquartile range) 9.0 (5 to 17) 2.0 (0 to 5.5) <.0001
Diagnosis of arthritis, N, % 28 / 47 (56%) 15 / 54 (28%) 0.001
Chronic/static course, N (%) 20 / 47 (43%) 10 / 62 (16%) 0.002
Fibromyalgia diagnosis (ACR criteria), N (%) 13 / 47 (28%) 3 / 62 (5%) 0.001
ACR fibromyalgia tool score, Median (IQR) 10 (8 to 13) 5 (2.5 to 8) <.0001
  1. aT-test for normally distributed data, Wilcoxon rank sum test for non-normally distributed data (time between onset and first clinic appointment, and peak myofascial tender points), chi square test for categorical data, Fisher’s exact test for categorical data that violate chi square assumptions.
  2. Note: Eight patients were not assessed for arthritis