Fig. 1
From: Biomarkers associating endothelial dysregulation in pediatric-onset systemic lupus erythematous
Markers Associated with Disease Activity Using Cutoff level of SLEDAI 12 (active v.s. inactive). Almost all the markers (b, c, d, e) except ADAMTS13 (f) and Ang-1 (a) are higher in pSLE patients compared to healthy controls. Serum Tie2 (c), VEGF(d), and Thrombomodulin (e) are correlated with high disease activity in pSLE; Whereas, serum levels of ADAMTS13 (F) is significantly lower in active pSLE patients compared to inactive pSLE. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001