Table 2 Association between patient characteristics/JIA indicators and pain trajectories
|  | Average (mean (SD), no. (%), median (IQR)) | Association with … relative to low pain | |||||
|---|---|---|---|---|---|---|---|
| Â | Low pain | Variable pain | High pain | Variable pain | High pain | ||
|  | n = 45 | n = 30 | n = 22 | OR (95%CI) | P value | OR (95%CI) | P value |
Patient characteristics | |||||||
 Age at JIA onset | 9.51 (4.71) | 9.96 (4.88) | 9.40 (5.31) | 1.00 (0.88–1.15) | 0.98 | 1.08 (0.93–1.25) | 0.34 |
 Age at study onset | 16.19 (1.18) | 16.46 (1.16) | 16.76 (1.31) | 1.38 (0.86–2.21) | 0.19 | 1.56 (0.87–2.79) | 0.13 |
 Female sex (ref: male) | 24 (53.3%) | 13 (43.3%) | 18 (81.8%) | 0.50 (0.14–1.82) | 0.29 | 2.92 (0.53–16.15) | 0.22 |
JIA subtype (ref: polyarticular course) | |||||||
 Enthesitis Related | 15 (33.3%) | 13 (43.3%) | 4 (18.2%) | 1.35 (0.32–5.60) | 0.68 | 0.59 (0.09–3.72) | 0.57 |
 Oligoarticular | 4 (8.9%) | 1 (3.3%) | 1 (4.5%) | 0.69 (0.06–8.19) | 0.77 | 0.52 (0.03–8.79) | 0.65 |
Medications (ref: not in use for each type) | |||||||
 DMARDs | 27 (60.0%) | 22 (73,3%) | 18 (81.8%) | 1.35 (0.32–5.60) | 0.40 | 3.72 (0.78–17.69) | 0.098 |
 Biologics | 18 (40.0%) | 12 (40.0%) | 10 (45.5%) | 1.01 (0.32–3.18) | 0.98 | 1.90 (0.47–7.74) | 0.37 |
 Steroids | 4 (8.9%) | 7 (23.3%) | 5 (22.7%) | 1.11 (0.16–7.59) | 0.91 | 0.68 (0.08–5.79) | 0.73 |
JIA activity markers at study onset | |||||||
 PGA | 1.40 (2.11) | 3.11 (2.73) | 3.47 (2.31) | 1.22 (0.90–1.64) | 0.20 | 1.44 (1.03–2.02) | 0.033 |
No. of: | |||||||
 Active joints | 0 (0–1) | 1 (0–1) | 0 (0–2) | 0.73 (0.50–1.06) | 0.096 | 0.62 (0.40–0.97) | 0.035 |
 Swollen joints | 0 (0–0) | 1 (0–2.25) | 1 (0–3) | 1.59 (0.99–2.57) | 0.057 | 1.73 (1.02–2.95) | 0.044 |
 Limited joints | 0 (0–1) | 2 (0–3) | 2 (0–5) | 1.53 (1.04–2.26) | 0.033 | 1.57 (1.06–2.32) | 0.026 |