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Table 2 Methotrexate and biologic use and tapering in SJIA: physician practices, CARRA workgroup survey

From: Physician practices for withdrawal of medications in inactive systemic juvenile arthritis, Childhood Arthritis and Rheumatology Research Alliance (CARRA) survey

Medication Never use this CTP
% (n)
Stop immediately
% (n)
Taper over weeks to < 2 months
% (n)
Taper over 2–6 months
% (n)
Taper over > 6 months
% (n)
Methotrexate 19 (14) 7 (5) 4 (3) 35 (26) 35 (26)
Anakinra 5.3 (4) 9.3 (7) 25.3 (19) 38.7 (29) 21.3 (16)
Canakinumab 14.7 (11) 12 (9) 4 (3) 36 (27) 33.3 (25)
Rilonacept 69.3 (52) 2.7 (2) 2.7 (2) 16 (12) (9.3 (7)
Tocilizumab 2.7 (2) 4 (3) 6.7 (5) 46.7 (35) 40 (30)
  1. Abbreviation: SJIA Systemic juvenile idiopathic arthritis, CARRA Childhood Arthritis and Rheumatology Research Alliance, CTP Consensus treatment plan [4]