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Table 6 Clinical Characteristics, N = 167 (single injection)

From: Retrospective review of immobilization vs. immediate resumption of activity in patients with Oligoarticular juvenile idiopathic arthritis following knee injections

N(%) or Median (25th–75th)

 
 

All (N = 167)

No Reoccurrence of Arthritis (N = 112)

Arthritis Reoccurrence (N = 55)

P-value*

SMD

Joint swelling

  > 1 (vs 0)

161 (96%)

109 (97%)

52 (95%)

0.40

0.14

Joint tenderness

  > 1 (vs 0)

30 (18%)

20 (18%)

10 (18%)

0.96

0.01

Joint limited range of motion

  > 1 (vs 0)

95 (57%)

66 (59%)

29 (53%)

0.45

0.13

 Total joints active

   

0.99

0.21

 1

90 (54%)

59 (53%)

31 (56%)

  

 2

58 (35%)

39 (35%)

19 (35%)

  

 3

13 (8%)

9 (8%)

4 (7%)

  

 4

4 (2%)

3 (3%)

1 (2%)

  

 5

0

2 (2%)

0

  

 6

2 (1%)

    

 2+ Joints Active (vs 1 only)

77 (46%)

53 (47%)

24 (44%)

0.65

0.07

 Pain Assessment (1–10)a

1 (0–4)

1.5 (0–4.0)

1 (0–3)

0.88

0.03

  CHAQ Scoreb

0.125 (0–0.50)

0.125 (0–0.500)

0 (0–0.313)

0.07

0.45

 MD Global Scorec

1(1–2)

2 (1–2)

1 (1–2)

0.11

0.36

 ANA status–Positive

108 (66%)

68 (62%)

40 (74%)

0.12

0.26

 RF status– Positive

4 (3%)

4 (4%)

0

0.30

0.29

 HLA-B27 status–Positive

14 (13%)

7 (11%)

7 (17%)

0.36

0.18

 ESRd

14 (8–23)

12 (8–20)

16 (8–26)

0.40

0.16

 On injection DMARDs

29 (17%)

19 (17%)

10 (18%)

0.85

0.03

 On injection biologics

7 (4%)

6 (5%)

1 (2%)

0.43

0.19

 On NSAIDs

109 (65%)

71 (63%)

38 (69%)

0.47

0.12

 Total joints injected

   

0.87

0.03

 2+

53 (32%)

36 (32%)

17 (31%)

  

 1

114 (68%)

76 (68%)

38 (69%)

  

 Steroid injection - Aristopan (vs. Kenalog)

156 (94%)

107 (96%)

49 (89%)

0.08

0.24

 Knee injection dose (mg)

10 (2–20)

10 (2–20)

10 (2–20)

0.33

0.16

 Knee injection dose (mg/kg)d

0.33 (0.10–0.78)

0.40 (0.10–0.77)

0.19 (0.10–0.84)

0.50

0.12

  1. *Wilcoxon Rank-Sum tests or Chi-Square/Fisher’s Exact Tests between arthritis reoccurrence yes/no, alpha = 0.05
  2. aPain Assessment is missing for 42% (n = 70) of the data (46% CHOP; 39% TSRH)
  3. bCHAQ score missing for 56% (n = 94) of the data (81% CHOP; 38% TSRH)
  4. cMD Global score missing for 46% (n = 77) of the data (74% CHOP; 25% TSRH)
  5. dESR score missing for 31% (n = 52) of the data
  6. SMD: standardized mean difference