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Table 6 Clinical Characteristics, N = 167 (single injection)

From: Retrospective review of immobilization vs. immediate resumption of activity in patients with Oligoarticular juvenile idiopathic arthritis following knee injections

N(%) or Median (25th–75th)  
  All (N = 167) No Reoccurrence of Arthritis (N = 112) Arthritis Reoccurrence (N = 55) P-value* SMD
Joint swelling
  > 1 (vs 0) 161 (96%) 109 (97%) 52 (95%) 0.40 0.14
Joint tenderness
  > 1 (vs 0) 30 (18%) 20 (18%) 10 (18%) 0.96 0.01
Joint limited range of motion
  > 1 (vs 0) 95 (57%) 66 (59%) 29 (53%) 0.45 0.13
 Total joints active     0.99 0.21
 1 90 (54%) 59 (53%) 31 (56%)   
 2 58 (35%) 39 (35%) 19 (35%)   
 3 13 (8%) 9 (8%) 4 (7%)   
 4 4 (2%) 3 (3%) 1 (2%)   
 5 0 2 (2%) 0   
 6 2 (1%)     
 2+ Joints Active (vs 1 only) 77 (46%) 53 (47%) 24 (44%) 0.65 0.07
 Pain Assessment (1–10)a 1 (0–4) 1.5 (0–4.0) 1 (0–3) 0.88 0.03
  CHAQ Scoreb 0.125 (0–0.50) 0.125 (0–0.500) 0 (0–0.313) 0.07 0.45
 MD Global Scorec 1(1–2) 2 (1–2) 1 (1–2) 0.11 0.36
 ANA status–Positive 108 (66%) 68 (62%) 40 (74%) 0.12 0.26
 RF status– Positive 4 (3%) 4 (4%) 0 0.30 0.29
 HLA-B27 status–Positive 14 (13%) 7 (11%) 7 (17%) 0.36 0.18
 ESRd 14 (8–23) 12 (8–20) 16 (8–26) 0.40 0.16
 On injection DMARDs 29 (17%) 19 (17%) 10 (18%) 0.85 0.03
 On injection biologics 7 (4%) 6 (5%) 1 (2%) 0.43 0.19
 On NSAIDs 109 (65%) 71 (63%) 38 (69%) 0.47 0.12
 Total joints injected     0.87 0.03
 2+ 53 (32%) 36 (32%) 17 (31%)   
 1 114 (68%) 76 (68%) 38 (69%)   
 Steroid injection - Aristopan (vs. Kenalog) 156 (94%) 107 (96%) 49 (89%) 0.08 0.24
 Knee injection dose (mg) 10 (2–20) 10 (2–20) 10 (2–20) 0.33 0.16
 Knee injection dose (mg/kg)d 0.33 (0.10–0.78) 0.40 (0.10–0.77) 0.19 (0.10–0.84) 0.50 0.12
  1. *Wilcoxon Rank-Sum tests or Chi-Square/Fisher’s Exact Tests between arthritis reoccurrence yes/no, alpha = 0.05
  2. aPain Assessment is missing for 42% (n = 70) of the data (46% CHOP; 39% TSRH)
  3. bCHAQ score missing for 56% (n = 94) of the data (81% CHOP; 38% TSRH)
  4. cMD Global score missing for 46% (n = 77) of the data (74% CHOP; 25% TSRH)
  5. dESR score missing for 31% (n = 52) of the data
  6. SMD: standardized mean difference