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Table 2 a Characteristics of typical KD patients responsive to IVIG therapy ( n = 42) and those unresponsive to a second dose of IVIG therapy ( n = 33). b Prevalence of the minor allele of rs563535954 in IVIG-unresponsive and IVIGresponsive KD patients

From: A low-frequency IL4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease

A

 

Patients with typical KD (n = 75)

   

IVIG responders

IVIG non-responders

   

(n = 42)

(n = 33)

   

Age at diagnosis (month)

 Mean (SD)

36.1 (21.9)

31.6 (18.3)

   

 Median (range)

33 (4–121)

30 (4–81)

   

Gender

   

 Male / Female

1.3

2.3

   

Principal symptoms ± CAL (%)

   

 4 symptoms + CAL

1 (2.4%)

3 (9.1%)

   

 5 or 6 symptoms - CAL

34 (81.0%)

16 (48.5%)

   

 5 or 6 symptoms + CAL

8 (16.7%)

14 (42.4%)

   

B

 

(n = 33)

(n = 42)

P value

IVIG-unresponsive KD

IVIG-responsive KD

C/T

C/C

C/T

C/C

rs563535954

4

29

0

42

0.0337

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Pediatric Rheumatology

ISSN: 1546-0096