Table 6 Comparison of epidemiology and characteristics of JIA-U in our results vs. in previous reports
study | our study | Saurenmann, 2007 [1] | Heiligenhaus, 2007 [2] | Nordal, 2017 [5] | Angeles-Han, 2015 [18] |
|---|---|---|---|---|---|
country | Japan | Switzerland | Germany | Norway | United States of America |
prevalence | 6.1% | 13.1% | 12% | 20.5% | 18% |
JIA subtype | |||||
oligo | 81.8% | 48% | 41% | 46.1% | 78.9% |
RF + poly | 0% | 0% | 0% | 0% | 0% |
Systemic | 0% | 0.6% | 0% | 0% | 0% |
Rate of uveitis in oligo | 16.1% | 20.9% | 17.6% | 19.6% | 30.8% |
Rate of uveitis in all other type | 1.6% | 8.3% | 6.7% | 21.3% | 7.1% |
Risk ratio of uveitis in oligo | 10 | 2.5 | 2.6 | 0.9 | 4.3 |
femalea | 67.6% vs. 70.5%, p = 0.743 | 79.6% vs. 63.7%, p = 0.0009b | 74% vs. 62%, p = 0.012 | 65.6% vs. 66.3% | 76.9% vs. 70.2%, p = 0.332 |
ANA-positive (%)a | 52.3% vs. 22.2%, p < 0.0001 | 80.9% vs. 51%, p < 0.0001 | 86% vs. 42%, p < 0.01 | 42.5% vs. 23.2% | 54.9% vs. 35.9%, p = 0.017 |
RF-positive (%)a | 2.4% vs. 24.5%, p = 0.0004 | – | – | 1.1% vs. 2.7% | 0% vs. 11.1%, p = 0.013 |
the mean age of uveitis onset (yrs.) | 5.6 | 6.2 | 5.2 | 10.8(acute) and 3.2(chronic) | median 4.8 |
the mean age of arthritis onset (yrs.)a | 3.8 vs. 6.8 | 4.3 vs. 7.3 | 3.8 vs. 7.0 | – | median 2.8 vs. 7.7 |
time from arthritis onset to uveitis diagnosis | median 2 yrs. | mean 1.8 yrs. | median 5.5 months | – | – |
uveitis diagnosis before the arthritis diagnosis | 4.9% | 12.7% | 10% | – | 24% |
anterior uveitis | 79.3% | 100% | 83% | – | 80% |
bilateral uveitis | 53.7% | 60.6% | 70% | – | 72% |
asymptomatic uveitis | 58.5% | 69.7% | – | – | – |