Variable | Phase 1 (n = 10) | Phase 2 (n = 20) | p-value* |
---|---|---|---|
Mean age in years on date of interview (SD) | 12.7 (1.5) | 13.1 (2.0) | 1.00 |
Female | 5 (50%) | 10 (50%) | NS |
Type of JIA | |||
 Polyarthritis | 3 | 4 |  |
 Oligoarthritis | 3 | 11 |  |
 Monoarthritis | 0 | 1 |  |
 Psoriatic arthritis | 2 | 1 |  |
 Systemic arthritis | 1 | 2 |  |
 Spondyloarthritis/enthesitis | 1 | 1 |  |
Mean duration of JIA, years (SD) | 7.2 (4.1) | 6.2 (4.7) | 0.53 |
Median disease Activity, JADAS71 | 4.8 (0.4–9.4)b,a | 4.5 (2.7–9.0)c,a | 0.70 |
 Inactive disease activity | 3 | 3 |  |
 Low disease activity | 0 | 1 |  |
 Moderate disease activity | 3 | 2 |  |
 High disease activity | 3 | 12 |  |
Number of active joints per child | 2 (0–4)b,a | 1 (0.25–2)d,a | 0.76 |
Number of active joints in the lower extremity per child | 2 (0–2)b,a | 1 (0–2)d,a | 0.80 |
Number of joints with restricted range-of-motion | 0 (0–0)b,a | 0 (0–0)d,a | 0.45 |
Number of joints with restricted range-of-motion in lower extremity per child | 0 (0–0)b,a | 0 (0–0)d,a | 0.80 |
Medications | |||
 Steroids | 0 | 1 |  |
 Biologic and Steroids | 2 | 0 |  |
 Biologic and DMARDs | 6 | 1 |  |
 Biologic | 1 | 4 |  |
 NSAIDs | 1 | 5 |  |
 DMARDs | 0 | 6 |  |
 No medication | 0 | 3 |  |
Mean KOOS Sports Score (SD) | 0.6 (0.7)b | 1.0 (0.7)c | 0.69 |