Fig. 1

a. Integration of CpG marker methylation patterns and gene expression profiles of CD177. The methylation patterns of the representative CpG marker (cg22537604) and gene expression profiles showed negative tendencies and were observed to change in both the healthy and febrile control subjects, as well as Kawasaki disease (KD) patients before and after undergoing intravenous immunoglobulin treatment. The histogram and curve are presented as mean ± standard error. b. We adopted scatter plots to represent the relationship between mRNA levels and DNA methylation, which demonstrate that mRNA levels were negatively correlated with DNA methylation (Pearson’s correlation coefficient r = − 0.562, p < 0.001)