Table 1 (abstract P1053). Demographic, clinical and genetic features of the study groups
From: 10th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID)
|  | ≥40 years n=50 | ≤20 years n= 100 | p |
|---|---|---|---|
Sex (F:M); present age (mean±SD) (yr) | 32:18; 57.2±7.9 | 62:38; 31.8±9.1 | NS; <0.001 |
Mean age at onset,(mean±sd) (yr) | 45.6±5.2 | 8.7±4.8 | <0.001 |
Mean age at diagnosis (mean ±sd) (yr) | 50.4±7.3 | 19.1±11.2 | <0.001 |
Delay in diagnosis (mean ±sd) (yr) | 4.8±5.5 | 10.4±11.8 | <0.001 |
Mean disease duration (mean ±sd) (yr) | 11.5±6.4 | 23.1±10.8 | <0.001 |
Abdominal pain, n (%) | 44(88) | 89(89.0) | NS |
Chest pain, n (%) | 7(14.0) | 27 (27.0) | NS |
Fever, n (%) | 30(60.0) | 81(81.0) | 0.005 |
Arthritis, n (%) | 12(24.0) | 33(33.0) | 0.25 |
Myalgia, n (%) | 1(2.0) | 12(12.0) | 0.04 |
Amyloidosis, n (%) | 1(2.0) | 3(3.0) | NS |
Positive family history, n (%) | 33(68.7) | 62 (65.2) | NS |
Response to colchicine, n (%) | 37(82.2) | 93 (94.8) | 0.014 |
M694VHomozygous, n (%) | 2(4.5) | 23(25.8) | 0.003 |
N of M694Vallelles | 24( 48 ) | 82 (82) | 0.014 |
No mutation, n (%) | 3(6.8) | 2(2.2) | NS |