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Table 2 The Oxford classification of IgA nephropathy (according to ref. [28])

From: Different histological classifications for Henoch-Schönlein purpura nephritis: which one should be used?

Histological variable Description
Mesangial hypercellularity M0 < 50% of glomeruli showing mesangial hypercellularity
M1 > 50% of glomeruli showing mesangial hypercellularity
Endocapillary hypercellularity E0 absent
E1 present
Segmental glomerulosclerosis/adhesion S0 absent
S1 present
presence or absence of podocyte hypertrophy/tip lesions in biopsies with S1
Tubular atrophy/interstitial fibrosis T0 ≤ 25% of the cortical area affected by tubular atrophy or interstitial fibrosis
T1 26–50% of the cortical area affected by tubular atrophy or interstitial fibrosis
T2 > 50% of the cortical area affected by tubular atrophy or interstitial fibrosis
Cellular/fibrocellular crescents C0 absent
C1 present in at least one glomerulus
C2 present in > 25% of glomeruli
  1. Modified with permission from Elsevier Ltd.©