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Table 1 Patient characteristics

From: Coronary artery status of patients with transient fever 24–36 h after first IVIG infusion did not differ from that seen in responsive patients

Characteristics

Group 1

n = 663

Group 2

n = 54

Group 3

n = 162

P value

1 vs 2

1 vs 3

2 vs 3

Age, years

2.43 ± 1.88

2.91 ± 1.91

2.85 ± 2.07

0.072

0.014

0.839

Male

378 (57.0)

29 (53.7)

107 (66.0)

0.670

0.041

0.108

Body weight, kg

12.9 ± 4.9

14.4 ± 5.1

14.1 ± 5.2

0.032

0.009

0.663

Height, cm

88.8 ± 16.7

93.0 ± 15.4

92.4 ± 16.2

0.075

0.016

0.784

Diagnostic criteria

 Conjunctivitis

640 (96.5)

50 (92.6)

154 (95.1)

0.138

0.361

0.500

 Red lips/oral mucosa

606 (91.4)

47 (87.0)

145 (89.5)

0.315

0.445

0.621

 Rash

566 (85.4)

50 (92.6)

147 (90.7)

0.159

0.075

0.788

 Cervical lymphadenopathy

406 (61.2)

38 (70.4)

111 (68.5)

0.194

0.103

0.866

 Changes in extremities

563 (84.9)

47 (87.0)

144 (88.9)

0.843

0.213

0.806

Complete presentation

565 (85.2)

48 (88.9)

144 (88.9)

0.551

0.258

1.000

BCG site reaction

313 (47.2)

21 (38.9)

66 (40.7)

0.259

0.159

0.873

Treatment duration, days

6.0 ± 1.2

5.8 ± 1.3

5.9 ± 1.2

0.174

0.441

0.424

Laboratory findings

 WBC, ×103/μL

14.6 ± 4.9

14.4 ± 4.8

14.3 ± 5.4

0.855

0.600

0.901

 Neutrophil, %

63.3 ± 13.9

66.6 ± 15.2

70.9 ± 14.0

0.094

< 0.001

0.061

 Hemoglobin, g/dL

11.3 ± 1.1

11.2 ± 1.0

11.2 ± 1.1

0.828

0.631

0.940

 Platelet, ×103/μL

338.0 ± 99.9

316.6 ± 89.4

322.8 ± 107.1

0.128

0.088

0.702

 Protein, g/dL

6.6 ± 0.7

6.7 ± 0.5

6.6 ± 0.8

0.835

0.795

0.732

 Albumin, g/dL

3.4 ± 0.5

3.4 ± 0.3

3.2 ± 0.5

0.636

< 0.001

0.010

 AST, IU/L

81.5 ± 140.6

140.6 ± 249.3

144.9 ± 284.7

0.006

< 0.001

0.922

 ALT, IU/L

93.5 ± 139.0

134.3 ± 209.1

150.59 ± 200.6

0.048

< 0.001

0.611

 Total bilirubin, mg/dL

0.72 ± 0.74

0.65 ± 0.50

1.21 ± 1.23

0.496

< 0.001

0.001

 Na+, mmol/L

136.1 ± 2.6

136.3 ± 2.6

135.3 ± 3.2

0.575

0.001

0.041

 C-reactive protein, mg/dL

8.63 ± 6.18

8.74 ± 7.16

10.91 ± 7.10

0.898

< 0.001

0.054

 BNP, pg/mL

108.0 ± 221.2

107.8 ± 286.3

143.9 ± 223.3

   

 Log-BNP

1.65 ± 0.56

1.55 ± 0.59

1.77 ± 0.58

0.264

0.023

0.027

 Pyuria

189 (28.5)

16 (29.6)

57 (35.2)

0.875

0.150

0.615

Coronary artery diameter during subacute phase

 LMCA, mm

2.33 ± 0.44

2.36 ± 0.40

2.48 ± 0.52

   

  Z score

1.02 ± 1.08

0.87 ± 1.02

1.24 ± 1.22

0.298

0.025

0.042

 LAD, mm

1.85 ± 0.40

1.83 ± 0.31

2.05 ± 0.67

   

  Z score

0.64 ± 1.07

0.38 ± 0.90

0.98 ± 1.40

0.083

0.001

0.004

 RCA, mm

1.83 ± 0.48

1.92 ± 0.34

2.03 ± 0.68

   

  Z score

0.37 ± 1.29

0.44 ± 0.85

0.73 ± 1.59

0.710

0.003

0.197

CAA on z score (subacute)

81 (12.2)

5 (9.3)

27 (16.7)

0.665

0.152

0.268

CAA on Japanese criteria (subacute)

37 (5.6)

1 (1.9)

11 (6.8)

0.350

0.574

0.302

Coronary artery diameter during conv. Phase

 LMCA, mm

2.24 ± 0.40

2.33 ± 0.38

2.35 ± 0.40

   

  Z score

0.70 ± 1.10

0.74 ± 1.10

0.84 ± 1.07

0.790

0.139

0.552

 LAD, mm

1.79 ± 0.33

1.86 ± 0.24

1.92 ± 0.53

   

  Z score

0.42 ± 1.02

0.46 ± 0.67

0.59 ± 1.14

0.796

0.076

0.440

 RCA, mm

1.76 ± 0.36

1.80 ± 0.32

1.92 ± 0.65

   

  Z score

0.07 ± 1.07

0.00 ± 0.89

0.32 ± 1.50

0.630

0.014

0.135

CAA on z score (conv.)

38 (5.7)

5 (9.3)

20 (12.3)

0.363

0.006

0.681

CAA on Japanese criteria (conv.)

16 (2.4)

1 (1.9)

7 (4.3)

1.000

0.187

0.683

  1. Data are reported as mean ± standard deviation, or number (%)
  2. WBC white blood cell, ESR erythrocyte sedimentation rate, AST aspartate aminotransferase, ALT alanine aminotransferase, BNP brain natriuretic peptide, LMCA left main coronary artery, LAD left anterior descending, RCA right coronary artery, CAA coronary artery aneurysm, conv. convalescent