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Table 1 Patient characteristics

From: Coronary artery status of patients with transient fever 24–36 h after first IVIG infusion did not differ from that seen in responsive patients

Characteristics Group 1
n = 663
Group 2
n = 54
Group 3
n = 162
P value
1 vs 2 1 vs 3 2 vs 3
Age, years 2.43 ± 1.88 2.91 ± 1.91 2.85 ± 2.07 0.072 0.014 0.839
Male 378 (57.0) 29 (53.7) 107 (66.0) 0.670 0.041 0.108
Body weight, kg 12.9 ± 4.9 14.4 ± 5.1 14.1 ± 5.2 0.032 0.009 0.663
Height, cm 88.8 ± 16.7 93.0 ± 15.4 92.4 ± 16.2 0.075 0.016 0.784
Diagnostic criteria
 Conjunctivitis 640 (96.5) 50 (92.6) 154 (95.1) 0.138 0.361 0.500
 Red lips/oral mucosa 606 (91.4) 47 (87.0) 145 (89.5) 0.315 0.445 0.621
 Rash 566 (85.4) 50 (92.6) 147 (90.7) 0.159 0.075 0.788
 Cervical lymphadenopathy 406 (61.2) 38 (70.4) 111 (68.5) 0.194 0.103 0.866
 Changes in extremities 563 (84.9) 47 (87.0) 144 (88.9) 0.843 0.213 0.806
Complete presentation 565 (85.2) 48 (88.9) 144 (88.9) 0.551 0.258 1.000
BCG site reaction 313 (47.2) 21 (38.9) 66 (40.7) 0.259 0.159 0.873
Treatment duration, days 6.0 ± 1.2 5.8 ± 1.3 5.9 ± 1.2 0.174 0.441 0.424
Laboratory findings
 WBC, ×103/μL 14.6 ± 4.9 14.4 ± 4.8 14.3 ± 5.4 0.855 0.600 0.901
 Neutrophil, % 63.3 ± 13.9 66.6 ± 15.2 70.9 ± 14.0 0.094 < 0.001 0.061
 Hemoglobin, g/dL 11.3 ± 1.1 11.2 ± 1.0 11.2 ± 1.1 0.828 0.631 0.940
 Platelet, ×103/μL 338.0 ± 99.9 316.6 ± 89.4 322.8 ± 107.1 0.128 0.088 0.702
 Protein, g/dL 6.6 ± 0.7 6.7 ± 0.5 6.6 ± 0.8 0.835 0.795 0.732
 Albumin, g/dL 3.4 ± 0.5 3.4 ± 0.3 3.2 ± 0.5 0.636 < 0.001 0.010
 AST, IU/L 81.5 ± 140.6 140.6 ± 249.3 144.9 ± 284.7 0.006 < 0.001 0.922
 ALT, IU/L 93.5 ± 139.0 134.3 ± 209.1 150.59 ± 200.6 0.048 < 0.001 0.611
 Total bilirubin, mg/dL 0.72 ± 0.74 0.65 ± 0.50 1.21 ± 1.23 0.496 < 0.001 0.001
 Na+, mmol/L 136.1 ± 2.6 136.3 ± 2.6 135.3 ± 3.2 0.575 0.001 0.041
 C-reactive protein, mg/dL 8.63 ± 6.18 8.74 ± 7.16 10.91 ± 7.10 0.898 < 0.001 0.054
 BNP, pg/mL 108.0 ± 221.2 107.8 ± 286.3 143.9 ± 223.3    
 Log-BNP 1.65 ± 0.56 1.55 ± 0.59 1.77 ± 0.58 0.264 0.023 0.027
 Pyuria 189 (28.5) 16 (29.6) 57 (35.2) 0.875 0.150 0.615
Coronary artery diameter during subacute phase
 LMCA, mm 2.33 ± 0.44 2.36 ± 0.40 2.48 ± 0.52    
  Z score 1.02 ± 1.08 0.87 ± 1.02 1.24 ± 1.22 0.298 0.025 0.042
 LAD, mm 1.85 ± 0.40 1.83 ± 0.31 2.05 ± 0.67    
  Z score 0.64 ± 1.07 0.38 ± 0.90 0.98 ± 1.40 0.083 0.001 0.004
 RCA, mm 1.83 ± 0.48 1.92 ± 0.34 2.03 ± 0.68    
  Z score 0.37 ± 1.29 0.44 ± 0.85 0.73 ± 1.59 0.710 0.003 0.197
CAA on z score (subacute) 81 (12.2) 5 (9.3) 27 (16.7) 0.665 0.152 0.268
CAA on Japanese criteria (subacute) 37 (5.6) 1 (1.9) 11 (6.8) 0.350 0.574 0.302
Coronary artery diameter during conv. Phase
 LMCA, mm 2.24 ± 0.40 2.33 ± 0.38 2.35 ± 0.40    
  Z score 0.70 ± 1.10 0.74 ± 1.10 0.84 ± 1.07 0.790 0.139 0.552
 LAD, mm 1.79 ± 0.33 1.86 ± 0.24 1.92 ± 0.53    
  Z score 0.42 ± 1.02 0.46 ± 0.67 0.59 ± 1.14 0.796 0.076 0.440
 RCA, mm 1.76 ± 0.36 1.80 ± 0.32 1.92 ± 0.65    
  Z score 0.07 ± 1.07 0.00 ± 0.89 0.32 ± 1.50 0.630 0.014 0.135
CAA on z score (conv.) 38 (5.7) 5 (9.3) 20 (12.3) 0.363 0.006 0.681
CAA on Japanese criteria (conv.) 16 (2.4) 1 (1.9) 7 (4.3) 1.000 0.187 0.683
  1. Data are reported as mean ± standard deviation, or number (%)
  2. WBC white blood cell, ESR erythrocyte sedimentation rate, AST aspartate aminotransferase, ALT alanine aminotransferase, BNP brain natriuretic peptide, LMCA left main coronary artery, LAD left anterior descending, RCA right coronary artery, CAA coronary artery aneurysm, conv. convalescent