Skip to main content

Table 4 Multilevel modelling analysis

From: The effectiveness of a multidisciplinary intervention strategy for the treatment of symptomatic joint hypermobility in childhood: a randomised, single Centre parallel group trial (The Bendy Study)

  Child’s pain assessment Parent’s pain assessment Parent-reported physical function Child reported HRQoL Coordination Grip strength
Unconditional time effect −1.40 (−1–66, − 1.13) −6.44 (− 12.0, −0.88) −0.0115 (− 0.121, 0.0979) 0.00992 (− 0.0142, 0.0340) 5.51 (0.0373, 11.0) 5.56 (2.00, 9.12)
Added univariate effects       
Intervention (vs. standard care) −0.106 (− 0.630, 0.420) 0.056 (−11.4, 11.5) −0.0639 (− 0.174, 0.302) 0.0146 (− 0.0311, 0.0600) −5.74 (− 16.2, 7.74) −2.49 (− 9.79, 4.81)
Age 9–12 (vs. 5–8)) 0.475 (− 0.109, 1.06) −6.99 (− 19.4, 5.45) −0.101 (− 0.365, 0.164) 0.0155 (− 0.0364, 0.0674) −3.55 (− 14.5, 7.37) −0.642 (−7.41. 6.13)
Age 13–16 (vs. 5–8)) 0.583 (− 0.135, 1.30) − 12.99 (− 29.4, 4.18) −0.0288 (− 0.316, 0.258) 0.0238 (− 0.0281, 0.0756) 3.65 (− 13.5, 20.8) 1.71 (−9.80, 13.2)
Female Sex (vs. Male) 0.426 (0.093,0.946) −3.75 (− 15.5, 7.96) −0.0702 (− 0.327, 0.187) 0.0304 (− 0.0435, 0.0900) 2.80 (− 7.78, 13.4) −2.43 (− 9.77, 4.90)
BMI 0.062 (− 0.029, 0.153) −0.33 (− 2.07, 1.41) −0.00521(− 0.0220, 0.0324) 0.00306 (− 0.00345,0.00957) −0.147 (− 1.73, 1.44) 0.806 (− 0.596, 2.21)
Beighton 0.013 (−-0.186, 0.212) −0.48 (−4.88, 3.92 0.0154 (− 0.0762, 0.107) −0.00305 (− 0.0188, 0.0127) 1.01 (−2.25, 4.27) −0.0259 (− 2.67, 2.62)
Baseline child pain − 0.768 (−1.05, − 0.486) −3.35(− 7.31, 0.61) 0.0130 (− 0.0943, 0.0685) 0.0118 (− 0.00510, 0.0288) 1.07 (−2.41, 4.54) −0.360 (− 2.46, 1.74)
  1. Figures represent regression coefficients (95% CI) and indicate rate of change in the outcome variable per year per unit change in child and parent pain. BMI, and Beighton score, and per category for sex and age. Figures in bold are statistically significant at p < 0.05