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Table 1 Baseline characteristics of patients with CNO

From: Chronic non bacterial osteitis- a multicentre study

CHARACTERISTICS FEATURES NUMBER (%)
Age at diagnosis (median;IQR years)   10.7 (8.9 to 12.7)
Gender F/M;ratio   94/37;2.54
Clinical Characteristics Bone pain (n = 129) 118 (91.4%)
Swelling (n = 102) 50 (49.01%)
Fever (n = 79) 6 (7.59%)
Symmetrical symptoms (n = 125) 24 (19.2%)
Clinical unifocal involvement 92 (70.22%)
Synovitis 9 (6.87%)
Arthritis 9 (6.87%)
Hyperostosis 43 (32.82%)
Number of sites Clinical 1.29 (range 0–3)
Radiological 3.27 (range 1–13)
Extraosseous involvement Psoriasis 5 (3.87%)
Ulcerative colitis 1 (0.76%)
Pustulosis 10 (7.63%)
Investigations Raised inflammatory markers (n = 126) 50 (39.68%)
ANA positive (n = 26) 3 (11.53%)
HLA B27 positive (n = 15) 1 (6.66%)
Bone biopsy performed 73 (55.72%)
Positive culture (n = 3) from bone biopsy Coagulase negative staphylococcus: 2 (66.66%)
Staphylococcus aureus: 1 (33.33%)
Family history of- Psoriasis (n = 130) 20 (15.38%)
Inflammatory bowel disease (n = 130) 4 (3.07%)
Autoimmune disorders (n = 130) 6 (4.61%)