Table 1 Baseline characteristics of patients with CNO
CHARACTERISTICS | FEATURES | NUMBER (%) |
|---|---|---|
Age at diagnosis (median;IQR years) | 10.7 (8.9 to 12.7) | |
Gender F/M;ratio | 94/37;2.54 | |
Clinical Characteristics | Bone pain (n = 129) | 118 (91.4%) |
Swelling (n = 102) | 50 (49.01%) | |
Fever (n = 79) | 6 (7.59%) | |
Symmetrical symptoms (n = 125) | 24 (19.2%) | |
Clinical unifocal involvement | 92 (70.22%) | |
Synovitis | 9 (6.87%) | |
Arthritis | 9 (6.87%) | |
Hyperostosis | 43 (32.82%) | |
Number of sites | Clinical | 1.29 (range 0–3) |
Radiological | 3.27 (range 1–13) | |
Extraosseous involvement | Psoriasis | 5 (3.87%) |
Ulcerative colitis | 1 (0.76%) | |
Pustulosis | 10 (7.63%) | |
Investigations | Raised inflammatory markers (n = 126) | 50 (39.68%) |
ANA positive (n = 26) | 3 (11.53%) | |
HLA B27 positive (n = 15) | 1 (6.66%) | |
Bone biopsy performed | 73 (55.72%) | |
Positive culture (n = 3) from bone biopsy | Coagulase negative staphylococcus: 2 (66.66%) | |
Staphylococcus aureus: 1 (33.33%) | ||
Family history of- | Psoriasis (n = 130) | 20 (15.38%) |
Inflammatory bowel disease (n = 130) | 4 (3.07%) | |
Autoimmune disorders (n = 130) | 6 (4.61%) |