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Table 4 Adverse Events

From: Pilot study comparing the childhood arthritis and rheumatology research alliance consensus treatment plans for induction therapy of juvenile proliferative lupus nephritis

Patient

AE

Medications at time of AE

AE Grade

SAE

Timing

1

Depression with suicidal ideation

CYC, Mixed CS

3

Yes

Induction

2

Opportunistic infection

MMF, Mixed CS

2

Yes

Induction

3

Infusion reaction

CYC, Primarily IV CS

3

No

Induction

4

Steroid intolerance

MMF, Mixed CS

2

No

Induction

5

Hypertension

MMF, Mixed CS

3

Yes

Maintenance

6

Acute appendicitis

MMF

3

Yes

Maintenance

7

Chest pain

Mycophenolic acid, low-dose prednisone*

2

No

Maintenance

8

Gastroenteritis

MMF. low-dose prednisone*

2

No

Maintenance

9

Pyelonephritis

MMF, low-dose prednisone*

2

Yes

Maintenance

  1. Abbreviations: AE adverse event, CS corticosteroid, CYC cyclophosphamide, MMF mycophenolate mofetil, SAE Serious adverse event
  2. *Low-dose prednisone = 10 mg/day or less