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Table 2 Frequency of damage in the 12 organ systems and the items of the SLICC/ACR Damage Index

From: Risk factors for damage in childhood-onset systemic lupus erythematosus in Asians: a case control study

Disease damage by system/ organ at last follow up Frequency (%)
Ocular 9 (15.3%)
 Cataract 7 (11.9%)
 Retinal change or optic atrophy 2 (3.4%)
Neuropsychiatric 7 (11.9%)
 Cognitive impairment or major psychosis 3 (5.1%)
 Seizures requiring therapy for 6 months 3 (5.1%)
 Cerebrovascular accident ever 0
 Cranial or peripheral neuropathy 1 (1.7%)
 Transverse myelitis 0
Renal 2 (3.4%)
 Estimated or measured GFR < 50% 0
 Proteinuria (nephrotic range proteinuria) 0
 End-stage renal disease 2 (3.4%)
Pulmonary a 0
Cardiovascular 2 (3.4%)
 Angina or coronary artery bypass 0
 Myocardial infarction ever 0
 Cardiomyopathy (ventricular dysfunction) 2 (3.4%)
 Valvular disease 0
 Pericarditis for 6 months 0
Peripheral vascular 1 (1.7%)
 Claudication for 6 months 0
 Minor tissue loss 0
 Significant tissue loss ever 0
 Venous thrombosis with swelling, ulceration or venous stasis 1 (1.7%)
Gastrointestinal b 0
Musculoskeletal 7 (11.9%)
 Muscle atrophy or weakness 1 (1.7%)
 Deforming or erosive arthritis 0
 Osteoporosis with fracture or vertebral collapse 0
 Avascular necrosis (unilateral) 3 (5.1%)
 Bilateral avascular necrosis 3 (5.1%)
 Osteomyelitis 0
Skin 3 (5.1%)
 Scarring chronic alopecia 0
 Extensive scarring or panniculum other than scalp and pulp space 1 (1.7%)
 Skin ulceration for > 6 months 2 (3.4%)
Premature gonadal failure 0
Diabetes 0
Malignancy 0
  1. a Includes pulmonary hypertension, pulmonary fibrosis, shrinking lung, pleural fibrosis and pulmonary infarction
  2. b Includes Infarction or resection of bowel below duodenum, spleen, liver or gall bladder ever, mesenteric insufficiency, chronic peritonitis, stricture or upper gastrointestinal tract surgery ever