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Table 2 Complication Incidence Rates

From: Outcomes of non-infectious Paediatric uveitis in the era of biologic therapy

  Total Cohort JIA-Uveitis Idiopathic Uveitis
Eyes On Presentation
n = 234^ (%)
n/EY* Incidence Rate/EY
(CI 95%)
Eyes On Presentation
n = 118^ (%)
n/EY Incidence Rate/EY
(CI 95%)
Eyes On Presentation
n = 105^ (%)
n/EY Incidence Rate/EY
(CI 95%)
IU vs JIA-U Incidence
p = 0.05
Visual Impairment
  > 0.3 LogMAR 43 (18.4%) 39/830 0.05 (0.03–0.06) 22 (18.6%) 27/529 0.05 (0.04–0.07) 18 (17.1%) 11/260 0.04 (0.02–0.08) 0.69
  ≥ 1.0 LogMAR 10 (4.3%) 14/1034 0.01 (0.01–0.02) 7 (5.9%) 10/652 0.02 (0.01–0.03) 3 (2.9%) 2/335 0.01 (0.00–0.02) 0.15
Ocular Complication
 Cataract 17 (7.3%) 47/939 0.05 (0.04–0.07) 11 (9.3%) 31/578 0.05 (0.04–0.08) 5 (4.8%) 12/317 0.04 (0.02–0.07) 0.24
 Raised IOP 19 (8.1) 22/986 0.02 (0.02–0.04) 13 (11%) 17/606 0.03 (0.02–0.05) 6 (5.7%) 3/327 0.01 (0.00–0.03) 0.05
 Glaucoma 0 15/1062 0.01 (0.01–0.02) 0 15/657 0.02 (0.01–0.04) 0 0/352   0.002
 Posterior Synechiae 43 (18.4%) 21/860 0.02 (0.02–0.04) 23 (19.5%) 17/524 0.03 (0.02–0.05) 18 (17.1%) 4/296 0.01 (0.01–0.04) 0.14
 Macular Oedema 7 (3%) 14/1027 0.01 (0.01–0.02) 3 (2.5%) 4/681 0.01 (0.00–0.02) 4 (3.8%) 9/293 0.02 (0.02–0.06) 0.01
 Band Keratopathy 19 (8.1%) 20/938 0.02 (0.01–0.03) 15 (12.7%) 12/586 0.02 (0.01–0.04) 3 (2.9%) 6/314 0.02 (0.01–0.04) 0.77
 Hypotony 4 (1.7%) 3/1084 0.00 (0.00–0.01) 3 (2.5%) 2/686 0.00 (0.00–0.01) 1 (1%) 0/347   0.31
 Optic Disc Swelling 23 (9.8%) 3/1012 0.00 (0.00–0.01) 2 (1.7%) 2/690 0.00 (0.00–0.01) 19 (18.1%) 1/279 0.00 (0.00–0.03) 0.81
 Vitreous Haemorrhage 0 1/1108 0.00 (0.00–0.01) 0 1/703 0.00 (0.00–0.01) 0 0/352   0.68
 Epiretinal Membrane 1 (0.4%) 1/1107 0.00 (0.00–0.01) 0 0/707 0.00 1 (1%) 0/349   0.68
Surgical Procedure
 Cataract Removal 2 (0.9%) 22/1038 0.02 (0.01–0.03) 2 (1.7%) 18/639 0.03 (0.02–0.04) 0 3/350 0.01 (0.00–0.03) 0.04
 Trabeculectomy 0 11/1087 0.01 (0.01–0.02) 0 11/682 0.02 (0.01–0.03) 0 0/352   0.01
 Vitrectomy 2 (0.9%) 8/1074 0.01 (0.00–0.01) 2 (1.7%) 4/673 0.01 (0.00–0.02) 0 4/348 0.01 (0.00–0.03) 0.32
 Laser Capsulotomy 0 3/1112 0.00 (0.00–0.01) 0 3/707 0.00 (0.00–0.01) 0 0/352   0.32
 Iridectomy 0 2/1107 0.00 (0.00–0.01) 0 2/702 0.00 (0.00–0.01) 0 0/352   0.47
  1. *n/EY – Number of new events/Number of Eye Years of Follow up
  2. ^ Within the cohort 293 eyes were affected. However, not all children had baseline presentation data available