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Table 1 (abstract O14). Most frequent events of special interest ordered by decreasing frequencies. Data are absolute numbers and frequencies (%)

From: Proceedings of the 25th European Paediatric Rheumatology Congress (PReS 2018)

  Pharmachild N = 2,022 (%) BiKeR N=1,697 (%)
Infections: 1523 (75.3) 1509 (89)
 Serious/targeted infections (Epstein‐Barr virus, cytomegalovirus, papilloma virus, herpes zoster primary and reactivation, and opportunistic infections) 674 (33.3) 171 (10.1)
 Tuberculosis 27 (1,3) 0
 Other infections 822 (40.6) 1338 (78.8)
Infusion/injection related reactions: 218 (10.8) 24 (1.4)
 Infusion related reaction 144 (7.1) 11 (0.6)
 Injection related reaction 74 (3.7) 13 (0.8)
Blood cells related ESI: 188 (9.3) 90 (5.3)
 Pancytopenia 6 (0.3) 65 (3.8)
 Neutropenia 107 (5.3) 14 (0.8)
 Macrophage activation syndrome 75 (3.7) 11 (0.6)
 Aplastic anemia 0 0
Autoimmune ESI: 50 (2.5) 50 (2.9)
 Inflammatory Bowel Disease (IBD) 21 (1.1) 23 (1.3)
 Other autoimmune diseases excluding IBD, uveitis and  demyelinisation disorders 18 (0.9) 24 (1.4)
 Lupus erythematosus systemic/lupus-like syndrome 4 (0.2) 1 (0.1)
 Optic neuritis 4 (0.2) 0
 Multiple sclerosis 2 (0.1) 0
 Demyelination 1 (0.05) 2 (0.2)
Malignancies: 16 (0.8) 13 (0.8)
 Leukaemias 3 (0.1) 2 (0.2)
 Lymphomas 2 (0.1) 5 (0.3)
 Haematopoietic neoplasms (excluding leukaemias and lymphomas) 1 (0.05) 2 (0.2)
 Neoplasm (other) 10 (0.5) 4 (0.2)