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Table 1 (abstract P082). Baseline clinical and biomarker levels

From: Proceedings of the 25th European Paediatric Rheumatology Congress (PReS 2018)

Parameter

Responders (n=20)

Non-responders (n=14)

p value*

Age at onset (months), median (IQR)

72(36,132)

87(30,108)

0.84

Mean delay in diagnosis (months), median (IQR)

21(4,59)

30(18,54)

0.326

JIA Subcategory, n

 SJIA

3

0

0.179

 Oligoarticular

3

6

 Polyarticular (RF+)

0

1

 Polyarticular (RF-)

6

2

 Entesitis related arthritis

7

5

Serum MRP 8/14 (pg/ml), median (IQR)

117.7(87.4,155.8)

78.8(59,118)

0.027

Serum IL-6 (pg/ml), median (IQR)

20.3(16.5,23.7)

14(12.2,18.2)

0.019

Serum IL-2 (pg/ml), median (IQR)

126.5(45.9,134.5)

43(31.9,81.9)

0.21

Serum TNFa (pg/ml), median (IQR)

30.7(27.4,32.9)

32.4(37,28.3)

0.43

Serum IL-12 (pg/ml), median (IQR)

48.4(38.3,57.2)

45.5(34,82)

0.83

  1. * The p values are based on Wilcoxon signed-rank test for comparison of median between responders and non-responders