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Table 2 Distribution of MBL2 genotypes (rs1800450) in patients with history of RF and controls

From: MBL2 gene polymorphism rs1800450 and rheumatic fever with and without rheumatic heart disease: an Egyptian pilot study

 

Controls

(n = 80)

RF (n = 160)

p

OR

95% CI

 

Without RHD

(n = 80)

With RHD

(n = 80)

Genotypes

      

AA n (%)

44 (55)

42 (52.5)

69 (86.25)

1.00 a

0.90

0.37–2.17

0.0003 b

5.13*

2.10–12.5

AB n (%)

24 (30)

34 (42.5)

11 (13.75)

0.50 a

1.48

0.57–3.84

0.02 b

0.29*

0.11–75.0

BB n (%)

12 (15)

4 (5)

0 (0)

0.26 a

0.29

0.06–1.58

0.001 b

0.03*

0.002–0.60

HWE

χ2 = 3.3, p > 0.05

χ2 = 0.38, p > 0.05

χ2 = 0.44, p > 0.05

   
  1. OR of AA: by comparison between AA versus (AB+BB) (dominant model)
  2. OR of AB: by comparison between AB versus AA (co-dominant model)
  3. OR of BB: by comparison between BB versus (AA+AB) (recessive model)
  4. a RF without RHD versus controls. b RF with RHD versus controls
  5. * significant difference at p < 0.05
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Pediatric Rheumatology

ISSN: 1546-0096