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Table 2 Distribution of MBL2 genotypes (rs1800450) in patients with history of RF and controls

From: MBL2 gene polymorphism rs1800450 and rheumatic fever with and without rheumatic heart disease: an Egyptian pilot study

  Controls
(n = 80)
RF (n = 160) p OR 95% CI
  Without RHD
(n = 80)
With RHD
(n = 80)
Genotypes       
AA n (%) 44 (55) 42 (52.5) 69 (86.25) 1.00 a 0.90 0.37–2.17
0.0003 b 5.13* 2.10–12.5
AB n (%) 24 (30) 34 (42.5) 11 (13.75) 0.50 a 1.48 0.57–3.84
0.02 b 0.29* 0.11–75.0
BB n (%) 12 (15) 4 (5) 0 (0) 0.26 a 0.29 0.06–1.58
0.001 b 0.03* 0.002–0.60
HWE χ2 = 3.3, p > 0.05 χ2 = 0.38, p > 0.05 χ2 = 0.44, p > 0.05    
  1. OR of AA: by comparison between AA versus (AB+BB) (dominant model)
  2. OR of AB: by comparison between AB versus AA (co-dominant model)
  3. OR of BB: by comparison between BB versus (AA+AB) (recessive model)
  4. a RF without RHD versus controls. b RF with RHD versus controls
  5. * significant difference at p < 0.05