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Table 4 Risk factors for sacroiliitis and active disease

From: Clinical features of children with enthesitis-related juvenile idiopathic arthritis / juvenile spondyloarthritis followed in a French tertiary care pediatric rheumatology centre

  Sacroiliitis Active disease at the last follow up
  Odds Ratio (CI 95%) p Odds Ratio (CI 95%) p
  Univariate analysis
Boys 0.7 (0.3–1.6) 0.41 0.3 (0.1–0.7) 0.01
HLA-B27 0.8 (0.3–1.9) 0.67 0.9 (0.4–2.1) 0.84
Age > 12 years 1.7 (0.6–4.9) 0.31 0.4 (0.1–1.1) 0.07
Familial history of SpA 3.6 (1.6–8.2) 0.02 3.1 (1.4–7.1) 0.01
Oligo-articular involvement at first consultation 0.5 (0.2–1.0) 0.06 0.5 (0.2–1.0) 0.06
Hip Arthritis 1.2 (0.6–2.5) 0.66 1.4 (0.7–2.9) 0.39
Enthesitis 4.7 (1.3–17.5) 0.01 1.7 (0.6–4.5) 0.32
Extra-articular involvement 1.2 (0.5–2.6) 0.69 1 (0.5–2.2) 1
  Multivariable analysis
Boys 0.94 (0.4–2.3) 0.82 0.44 (0.2–1.1) 0.06
Age > 12 years 2.61 (08–8.8) 0.09 0.48 (0.1–1.6) 0.22
Familial history of SpA 3.61 (1.5–8.7) < 0.01 2.98 (1.2–7.3) 0,02
Enthesitis 4.2 (1.1–16.6) 0.04 1.55 (0.5–4.9) 0.45
Oligo-articular involvement at first consultation 0.47 (0.2–1.2) 0.10 0.73 (0.3–1.7) 0.46
  1. CI confidence interval
  2. We studied the five factors (male gender, age > 12 years at disease onset, familial history of SpA, presence of enthesitis, and oligo-articular involvement at first consultation) associated with at least one of our judgment criteria for the multivariable analysis