Clinical features of children with enthesitis-related juvenile idiopathic arthritis / juvenile spondyloarthritis followed in a French tertiary care pediatric rheumatology centre

Table 4 Risk factors for sacroiliitis and active disease

	Sacroiliitis		Active disease at the last follow up
	Odds Ratio (CI 95%)	p	Odds Ratio (CI 95%)	p
	Univariate analysis
Boys	0.7 (0.3–1.6)	0.41	0.3 (0.1–0.7)	0.01
HLA-B27	0.8 (0.3–1.9)	0.67	0.9 (0.4–2.1)	0.84
Age > 12 years	1.7 (0.6–4.9)	0.31	0.4 (0.1–1.1)	0.07
Familial history of SpA	3.6 (1.6–8.2)	0.02	3.1 (1.4–7.1)	0.01
Oligo-articular involvement at first consultation	0.5 (0.2–1.0)	0.06	0.5 (0.2–1.0)	0.06
Hip Arthritis	1.2 (0.6–2.5)	0.66	1.4 (0.7–2.9)	0.39
Enthesitis	4.7 (1.3–17.5)	0.01	1.7 (0.6–4.5)	0.32
Extra-articular involvement	1.2 (0.5–2.6)	0.69	1 (0.5–2.2)	1
	Multivariable analysis
Boys	0.94 (0.4–2.3)	0.82	0.44 (0.2–1.1)	0.06
Age > 12 years	2.61 (08–8.8)	0.09	0.48 (0.1–1.6)	0.22
Familial history of SpA	3.61 (1.5–8.7)	< 0.01	2.98 (1.2–7.3)	0,02
Enthesitis	4.2 (1.1–16.6)	0.04	1.55 (0.5–4.9)	0.45
Oligo-articular involvement at first consultation	0.47 (0.2–1.2)	0.10	0.73 (0.3–1.7)	0.46

CI confidence interval
We studied the five factors (male gender, age > 12 years at disease onset, familial history of SpA, presence of enthesitis, and oligo-articular involvement at first consultation) associated with at least one of our judgment criteria for the multivariable analysis