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Table 4 Risk factors for sacroiliitis and active disease

From: Clinical features of children with enthesitis-related juvenile idiopathic arthritis / juvenile spondyloarthritis followed in a French tertiary care pediatric rheumatology centre

 

Sacroiliitis

Active disease at the last follow up

 

Odds Ratio (CI 95%)

p

Odds Ratio (CI 95%)

p

 

Univariate analysis

Boys

0.7 (0.3–1.6)

0.41

0.3 (0.1–0.7)

0.01

HLA-B27

0.8 (0.3–1.9)

0.67

0.9 (0.4–2.1)

0.84

Age > 12 years

1.7 (0.6–4.9)

0.31

0.4 (0.1–1.1)

0.07

Familial history of SpA

3.6 (1.6–8.2)

0.02

3.1 (1.4–7.1)

0.01

Oligo-articular involvement at first consultation

0.5 (0.2–1.0)

0.06

0.5 (0.2–1.0)

0.06

Hip Arthritis

1.2 (0.6–2.5)

0.66

1.4 (0.7–2.9)

0.39

Enthesitis

4.7 (1.3–17.5)

0.01

1.7 (0.6–4.5)

0.32

Extra-articular involvement

1.2 (0.5–2.6)

0.69

1 (0.5–2.2)

1

 

Multivariable analysis

Boys

0.94 (0.4–2.3)

0.82

0.44 (0.2–1.1)

0.06

Age > 12 years

2.61 (08–8.8)

0.09

0.48 (0.1–1.6)

0.22

Familial history of SpA

3.61 (1.5–8.7)

< 0.01

2.98 (1.2–7.3)

0,02

Enthesitis

4.2 (1.1–16.6)

0.04

1.55 (0.5–4.9)

0.45

Oligo-articular involvement at first consultation

0.47 (0.2–1.2)

0.10

0.73 (0.3–1.7)

0.46

  1. CI confidence interval
  2. We studied the five factors (male gender, age > 12 years at disease onset, familial history of SpA, presence of enthesitis, and oligo-articular involvement at first consultation) associated with at least one of our judgment criteria for the multivariable analysis