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Table 5 Correlation between disease activity markers and the number of positive International League Against Rheumatism (ILAR) and Yamaguchi criteria in AOSD patients

From: Application of the international league against rheumatism classification criteria for systemic juvenile idiopathic arthritis as a prognostic factor in patients with adults-onset Still’s disease

  Yamaguchi criteria ILAR criteria
  ρ P-value ρ P-value
Systemic score 0.437 < 0.0001 0.741 < 0.0001
Leukocytes 0.312 0.0003 −0.007 0.9369
Hemoglobin −0.062 0.4802 −0.092 0.2953
Platelets 0.155 0.0764 −0.102 0.2461
ESR 0.178 0.0406 0.115 0.1890
CRP 0.216 0.0128 0.237 0.0063
Ferritin 0.169 0.0534 0.055 0.5274
LDH −0.307 0.0056 −0.055 0.6290
Total bilirubin −0.150 0.0864 −0.002 0.9798
Albumin −0.156 0.0744 −0.281 0.0011
AST −0.104 0.2334 −0.035 0.6891
ALT −0.032 0.7151 −0.058 0.5064
  1. ESR erythrocyte sedimentation rate, CRP C-reactive protein, LDH lactate dehydrogenase, AST aspartate aminotransferase, ALT alanine aminotransferase. Systemic scores (0–12) were obtained using the method described by Pouchot et al. [8], with 1 point assigned for each of the following manifestations: fever, typical rash, pleuritis, pneumonia, pericarditis, hepatomegaly or abnormal liver function tests, splenomegaly, lymphadenopathy, leukocytosis ≥ 15,000/mm2, sore throat, myalgia, and abdominal pain. The Pearson correlation statistic was used to compare the correlation between ESR, CRP, ferritin, and leukocyte counts, as disease activity markers, and the Yamaguchi and ILAR criteria