Fig. 1

Treatment targets for the treatment of systemic juvenile idiopathic arthritis. Treatments should be reached sequentially. The physician global assessment is scored on a scale of 0 to 10, where 0 represents lack of any disease activity and 10 represents maximal disease activity. The juvenile arthritis disease activity score (JADAS)-10 represents the sum of 4 individual scores, namely the physician global assessment (range 0–10), the patient or parent global assessment (range 0–10), the active joint count (range 0–10), and the normalized erythrocyte sedimentation rate after 1 h ([observed rate - 20]/100, i.e. values up to 20 mm/h are scored as 0 and values equal to or above 120 mm/h are scored as 10) or C-reactive protein (CRP; [observed CRP in mg/l – 10]/100, i.e. values up to 10 mg/l are scored as 0 and values equal to or above 110 mg/l are scored as 10)