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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study

Fig. 2

Log-linear regression analysis of individual CL/F (L/h) of plasma toficitinib versus body weight and 90% confidence region. Regression equation ln(CL/F) = 3.5018 + 0.370973 × ln(weight/70). Weight has been standardized to an average adult weight of 70 kg first, then log-transformed. N = 8 for CL/F in Cohort 2 due to incomplete pharmacokinetics sampling for 1 patient. CL/F apparent plasma clearance

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Pediatric Rheumatology

ISSN: 1546-0096