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Table 3 Description of significantly higher activation clusters during unpredictable variable pain IMP group when compared to fixed pain

From: Functional resonance magnetic imaging (fMRI) in adolescents with idiopathic musculoskeletal pain: a paradigm of experimental pain

    MNI Coordinatesa
Localization Side Cluster Size x y z Z score p Value
1. Lingual Gyrus R 21,632 8 −52 2 3.86 <0.0001b
Extending to
 Precuneus Gyrus R   6 −56 8 3,63
 Cingulate gyrus R   4 −50 28 3,55
2. Prefrontal Cortex R 4654 2 −42 −24 3,37 <0.0001c
Extending to
 Subcallosal area R   6 30 −24 3,32
 Paracingulate Gyrus R   4 50 −8 3,2
3. Inferior temporal gyrus R 2626 46 10 −42 3,29 <0.0001d
Extending to
 Middle temporal gyrus –posterior R   56 −16 −16 3,04
 Superior temporal gyrus –posterior R   68 −10 −4 2,93
 Planum temporale R   42 −36 16 2,91 0.03
4. Precentral Gyrus R 866 48 −2 22 2,66
Extending to
 Poscentral Gyrus R   66 −8 30 2,43
  1. aThe presented coordinates refer to the location of the maximum activation voxel within each cluster. bStatistical value p = 5.5e-30; cStatistical value p = 8.19e-10 dstatistical value p = 3.16e-06 (idem scientific notation Table 2)