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Table 3 Description of significantly higher activation clusters during unpredictable variable pain IMP group when compared to fixed pain

From: Functional resonance magnetic imaging (fMRI) in adolescents with idiopathic musculoskeletal pain: a paradigm of experimental pain

   

MNI Coordinatesa

Localization

Side

Cluster Size

x

y

z

Z score

p Value

1. Lingual Gyrus

R

21,632

8

−52

2

3.86

<0.0001b

Extending to

 Precuneus Gyrus

R

 

6

−56

8

3,63

 Cingulate gyrus

R

 

4

−50

28

3,55

2. Prefrontal Cortex

R

4654

2

−42

−24

3,37

<0.0001c

Extending to

 Subcallosal area

R

 

6

30

−24

3,32

 Paracingulate Gyrus

R

 

4

50

−8

3,2

3. Inferior temporal gyrus

R

2626

46

10

−42

3,29

<0.0001d

Extending to

 Middle temporal gyrus –posterior

R

 

56

−16

−16

3,04

 Superior temporal gyrus –posterior

R

 

68

−10

−4

2,93

 Planum temporale

R

 

42

−36

16

2,91

0.03

4. Precentral Gyrus

R

866

48

−2

22

2,66

Extending to

 Poscentral Gyrus

R

 

66

−8

30

2,43

  1. aThe presented coordinates refer to the location of the maximum activation voxel within each cluster. bStatistical value p = 5.5e-30; cStatistical value p = 8.19e-10 dstatistical value p = 3.16e-06 (idem scientific notation Table 2)