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Table 2 Estimates of the cumulative incidence (%) of growth delay, short stature, excessive weight gain and obesity within 1 and 3 years after diagnosis in seven JIA categories

From: Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort

JIA Category

Growth delay

Short stature

Excessive weight gain

Obesity

1-year cumulative incidence

(95% CI)

3-year cumulative incidence

(95% CI)

1-year cumulative incidence

(95% CI)

3-year cumulative incidence

(95% CI)

1-year cumulative incidence

(95% CI)

3-year cumulative incidence

(95% CI)

1-year cumulative Incidence

(95% CI)

3-year cumulative Incidence

(95% CI)

All (N = 1147)

3.2 (2.4, 4.5)

8.5 (6.8, 10.6)

1.2 (0.7, 2.1)

3.0 (2.1, 4.4)

4.8 (3.7, 6.2)

10.7 (8.8, 12.9)

5.2 (4.0, 6.9)

10.8 (8.8, 13.2)

Systemic arthritis (n = 77)

6.8 (2.9, 15.7)

22.5 (14.2, 34.7)

1.4 (0.2, 9.8)

9.3 (4.3, 19.7)

17.2 (10.4, 27.8)

28.1 (19.0, 40.3)

22.7 (13.9, 35.9)

34.4 (23.0, 49.4)

Oligoarthritis (n = 443)

3.8 (2.3, 6.1)

7.8 (5.3, 11.3)

1.2 (0.5, 2.9)

2.3 (1.2, 4.4)

3.8 (2.3, 6.1)

10.5 (7.6, 14.4)

3.3 (1.9, 5.7)

8.2 (5.5, 12.1)

RF-negative polyarthritis (n = 232)

4.0 (2.1, 7.6)

7.4 (4.5, 12.0)

0.9 (0.2, 3.6)

0.9 (0.2, 3.6)

3.6 (1.8, 7.0)

8.9 (5.6, 14.1)

3.5 (1.7, 7.2)

8.5 (5.2, 13.8)

RF-positive polyarthritis (n = 44)

---

9.9 (3.1, 28.7)

---

4.3 (0.6, 27.1)

9.1 (3.5, 22.6)

15.0 (7.2, 31.9)

---

5.9 (0.8, 35.0)

Psoriatic arthritis (n = 70)

2.9 (0.7, 10.9)

9.5 (4.0, 21.8)

2.9 (0.7, 11.1)

9.5 (3.9, 22.0)

3.0 (0.7, 11.4)

5.0 (1.6, 14.9)

4.1 (1.0, 15.5)

11.7 (5.0, 26.0)

Enthesitis-related arthritis (n = 164)

1.2 (0.3, 4.7)

7.2 (3.6, 14.4)

0.6 (0.1, 4.5)

1.6 (0.4, 6.3)

3.7 (1.7, 8.1)

8.3 (4.5, 14.9)

5.4 (2.6, 10.9)

9.7 (5.4, 17.2)

Undifferentiated (n = 117)

1.9 (0.5, 7.2)

5.7 (2.4, 13.5)

1.9 (0.5, 7.4)

3.6 (1.1, 11.4)

3.6 (1.4, 9.3)

7.6 (3.9, 14.7)

8.4 (4.3, 16.0)

14.1 (8.4, 23.1)

  1. Growth delay: a decrease of 1.0 or more in height Z-score relative to the z-score of that child at enrolment. Short stature: a height below the 2.5th percentile for age and sex. Excessive weight gain: an increase of 1.0 or more in BMI Z-score relative to the z-score of that child at enrolment. Obesity: a BMI above the 95th percentile for age and sex
  2. --- = Cumulative incidence could not be calculated as no child had experienced the growth impairment at this time