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Table 2 Demographic, serum inflammatory, and bone metabolic data and imaging findings

From: Bone metabolism and inflammatory characteristics in 14 cases of chronic nonbacterial osteomyelitis

 

group 1 (n = 10)

group 2 (n = 4)

p Value

Age (years)

10.3 (8.7–11.9)

12.7 (10.3–15.2)

0.09

Sex, female (%)

40

25

0.62

Time between first symptom to diagnosis (month)

8 (3.3–12.6)

9.2 (1.9–16.6)

0.76

CRP (mg/dL)

0.47 (0.01–1.23)

0.79 (0.01–1.79)

0.64

ESR (mm/h)

24.2 (6.6–41.8)

18.3 (9.6–46.1)

0.69

IgG (mg/dL)

943 (621–1266)

1607 (1097–2117)

<0.05

BAP (μg/L)

54.8 (36.3–73.4)

73.1 (43.8–102.4)

0.27

TRAP5b (mU/dL)

1205 (713–1696)

1095 (318–1871)

0.79

SUV max on FDG-PET

1.6 (1.1–4.1)

1.8 (1.1–4.1)

0.38

Number of bones with high accumulation on FDG-PET

4.2 (2.1–6.3)

6.3 (3.0–9.5)

0.27

Bone lesions with high signal on T2-STIR MRI

7.1 (1.2–13.0)

23.5 (14.2–32.8)

<0.01

Z score(−) of BMD

1.9 (1.2–2.6)

2.5 (1.3–3.7)

0.37

  1. Group 1, patients with response to first-line treatment; group 2, patients with no response to first-line treatment. All data in groups 1 and 2 indicate mean values (range)
  2. Abbreviations: CRP C-reactive protein, ESR erythrocyte sedimentation rate, IgG immunoglobulin G, BAP bone alkaline phosphatase, TRAP5b tartrate-resistant acid phosphatase serum; band 5, SUV max, maximum standardized uptake value, FDG-PET fluorodeoxyglucose-positron emission tomography, T2-STIR MRI T2-signal intensity in short tau inversion recovery magnetic resonance imaging, BMD bone mineral density