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Table 2 Demographic, serum inflammatory, and bone metabolic data and imaging findings

From: Bone metabolism and inflammatory characteristics in 14 cases of chronic nonbacterial osteomyelitis

  group 1 (n = 10) group 2 (n = 4) p Value
Age (years) 10.3 (8.7–11.9) 12.7 (10.3–15.2) 0.09
Sex, female (%) 40 25 0.62
Time between first symptom to diagnosis (month) 8 (3.3–12.6) 9.2 (1.9–16.6) 0.76
CRP (mg/dL) 0.47 (0.01–1.23) 0.79 (0.01–1.79) 0.64
ESR (mm/h) 24.2 (6.6–41.8) 18.3 (9.6–46.1) 0.69
IgG (mg/dL) 943 (621–1266) 1607 (1097–2117) <0.05
BAP (μg/L) 54.8 (36.3–73.4) 73.1 (43.8–102.4) 0.27
TRAP5b (mU/dL) 1205 (713–1696) 1095 (318–1871) 0.79
SUV max on FDG-PET 1.6 (1.1–4.1) 1.8 (1.1–4.1) 0.38
Number of bones with high accumulation on FDG-PET 4.2 (2.1–6.3) 6.3 (3.0–9.5) 0.27
Bone lesions with high signal on T2-STIR MRI 7.1 (1.2–13.0) 23.5 (14.2–32.8) <0.01
Z score(−) of BMD 1.9 (1.2–2.6) 2.5 (1.3–3.7) 0.37
  1. Group 1, patients with response to first-line treatment; group 2, patients with no response to first-line treatment. All data in groups 1 and 2 indicate mean values (range)
  2. Abbreviations: CRP C-reactive protein, ESR erythrocyte sedimentation rate, IgG immunoglobulin G, BAP bone alkaline phosphatase, TRAP5b tartrate-resistant acid phosphatase serum; band 5, SUV max, maximum standardized uptake value, FDG-PET fluorodeoxyglucose-positron emission tomography, T2-STIR MRI T2-signal intensity in short tau inversion recovery magnetic resonance imaging, BMD bone mineral density