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Table 1 Clinical, laboratory, and demographic features of patients with chronic nonbacterial osteomyelitis

From: Bone metabolism and inflammatory characteristics in 14 cases of chronic nonbacterial osteomyelitis

  Chief compliment Sex Age (years) The time between first symptom and diagnosis(months) Follow-up (months) CRP (mg/dL) ESR (mm/h) SAA (μg/mL) IgG (mg/dL) BAP (μg/L) TRAP5b (mU/dL) Number of bones with high accumulation on FDG-PET Bone lesions with high signal on T2-STIR MRI BMD(g/cm2) Z score Treatment Treatment response to first line therapy
1 Fever of unknown origin F 13 18 46 0.09 33 27 1722 37.4 338 8 33 0.921 −0.8 N + B no response
2 Pain in the left hand M 15 3 44 0.01 5 <5 1620 42.3 1870 8 24 0.726 −3.7 N no response
3 Pain in the right foot M 12 12 45 0.49 35 56 1524 82.8 1170 1 29 N/A N/A N no response
4 Pain in both femurs M 12 4 56 2.56 59 143 1561 53.5 1050 8 8 0.582 −2.1 N + B no response
5 Pain in both hands F 11 9 26 0.01 2 <5 802 30.2 239 2 10 0.667 −2.2 N + B clinical remission
6 Pain in the right foot M 12 5 48 0.01 1 <5 1057 62.8 1620 3 3 0.742 −1.5 N + B clinical remission
7 Fever of unknown origin F 15 3 52 0.4 18 26 1361 8.1 270 11 27 0.999 −0.3 N + B partial response
8 Pain in both knees F 5 2 33 0.02 7 <5 993 65.5 914 4 8 N/A N/A N + B clinical remission
9 Fever of unknown origin and pain in the left knee M 10 24 22 0.54 77 58 1561 49.49 2150 2 2 0.601 −1.4 N partial response
10 Pain in both feet and knees M 13 13 31 0.04 5 <5 1255 116.4 2430 4 4 0.688 −2.1 N + B partial response
11 Pain in both feet F 10 11 31 0.01 4 <5 1255 62.2 843 4 4 0.593 −2.8 N + B clinical remission
12 Pain in both feet M 12 4 32 0.19 16 14 1150 94.2 1500 5 2 0.505 −2.9 N + B partial response
13 Pain in the right foot M 8 5 29 0.01 2 6 1293 64.1 717 1 3 0.554 −1.9 N + B partial response
14 Pain in both feet and knees M 10 3 22 3.49 51 50 879 72 1320 6 8 0.513 −2.6 N + B partial response
Mean   Girls: 5 Boys: 9 11.3 8.3 37 0.6 23 48 1288 60 1174 4.8 11.8 0.7 −2.0 NSAIDs alone: 3 NSAIDs + Bisphosphonate: 11 Clinical remission: 4 Partial response: 6 No response: 4
  1. Abbreviations: F female, M male, CRP C-reactive protein, ESR erythrocyte sedimentation rate, SAA serum amyloid A, IgG immunoglobulin G, BAP bone alkaline phosphatase, TRAP5b tartrate-resistant acid phosphatase serum band 5bm, BMD bone mineral density, NNSAIDs, B Bisphosphonate