Fig. 4From: Bone metabolism and inflammatory characteristics in 14 cases of chronic nonbacterial osteomyelitisRepresentative case of a 5-year-old girl with CNO. The patient had a 3-month history of pain in both knees, and achieved clinical remission after the initial treatment. (a) Radiographic examination showed sclerosis in the distal metaphysis of both femurs. (b) FDG-PET image demonstrating increased multiple FDG uptakes in both distal femurs and right proximal tibia. (c) T2-STIR MRI scan at first presentation showing high signal in both distal femurs and right proximal tibia. (d) T2-STIR MRI scan at 6Â months after the initiation of first-line treatment showing remission of high signals in both femurs and right tibia. CNO, chronic nonbacterial osteomyelitis; FDG-PET, fluorodeoxyglucose-positron emission tomography; T2-STIR MRI, T2-signal intensity in short tau inversion recovery magnetic resonance imagingBack to article page