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Table 2 Dynamic of basic clinical and laboratory parameters among children with JIA starting treatment with etanercept (N = 197) at baseline and at the final measurement during 1 year follow-up

From: Predictors of the response to etanercept in patients with juvenile idiopathic arthritis without systemic manifestations within 12 months: results of an open-label, prospective study conducted at the National Scientific and Practical Center of Children's Health, Russia

Characteristics Baseline, median (IQR) 1 year follow-up, median (IQR)
Active joint count 4 (2-10) 0 (0-3)
 Persistent oligoarticular 2 (2-4) 0 (0-0)
 Extended oligoarticular 6 (5-10) 0 (0-0)
 Polyarticular RF- 14 (6-23.5) 0 (0-2)
 Enthesitis-related 5 (2.5-9) 0 (0-1.5)
Limited joint count 4 (2-11) 0 (0-2)
 Persistent oligoarticular 2 (2-3.5) 0 (0-0)
 Extended oligoarticular 6 (3-10) 0 (0-1)
 Polyarticular RF- 15 (6.5-25.5) 0 (0-6)
 Enthesitis-related 4.5 (4-9) 0 (0-1.5)
Swollen joint count 4 (2-8) 0 (0-0)
 Persistent oligoarticular 2 (2-4) 0 (0-0)
 Extended oligoarticular 6 (4-6) 0 (0-0)
 Polyarticular RF- 9 (5-12.5) 0 (0-2)
 Enthesitis-related 4 (2-7) 0 (0-0)
Pained joint count 4 (2-10) 0 (0-0)
 Persistent oligoarticular 2 (1.5-3) 0 (0-0)
 Extended oligoarticular 6 (3-9) 0 (0-0)
 Polyarticular RF- 12 (4-23) 0 (0-0)
 Enthesitis-related 4.5 (3-9) 0 (0-1)
Morning stiffness, min 30 (0-60) 0 (0-15)
 Persistent oligoarticular 30 (0-60) 0 (0-0)
 Extended oligoarticular 35 (0-60) 0 (0-3)
 Polyarticular RF- 60 (20-120) 0 (0-0)
 Enthesitis-related 60 (15-120) 0 (0-1)
Physician global of disease (0-100 mm) 60 (45-80) 5 (0-15)
 Persistent oligoarticular 50 (42-70) 0 (0-4)
 Extended oligoarticular 65 (46-80) 3 (0-14)
 Polyarticular RF- 70 (56-86) 6 (2-19)
 Enthesitis-related 68.5 (54.5-82.5) 4.5 (0.5-11)
Parent/patient global of well-being (0-100 mm) 68 (50-82.5) 6.5 (2.8-14.3)
 Persistent oligoarticular 60 (49-70) 2 (0-7)
 Extended oligoarticular 68 (50-81) 5 (3-10)
 Polyarticular RF- 73.5 (60-87) 9 (2-15.5)
 Enthesitis-related 70 (50-90) 4.5 (0-12)
Childhood health assessment questionnaire (0-3) 1.3 (0.5-1.9) 0 (0-0.2)
 Persistent oligoarticular 0.78 (0.5-1.5) 0 (0-0)
 Extended oligoarticular 1.5 (1-1.9) 0 (0-0.25)
 Polyarticular RF- 1.75 (13-2.25) 0 (0-0.75)
 Enthesitis-related 1.5 (0.75-2.5) 0 (0-0.25)
Juvenile arthritis disease activity score-71 19.2 (13.8-28.5) 1.1 (0.3-3.9)
 Persistent oligoarticular 14.9 (11.7-18.9) 0.5 (0-1.1)
 Extended oligoarticular 21.8 (16.3-28.5) 1 (0-2.5)
 Polyarticular RF- 29.6 (20.6-39.8) 1.45 (0.65-6.4)
 Enthesitis-related 20.6 (15.6-30.7) 1.1 (0.1-3.6)
Erythrocyte sedimentation rate, mm/h 21 (12-35) 5 (3-11)
 Persistent oligoarticular 19.5 (10-28) 5 (2-7)
 Extended oligoarticular 20 (15-35) 4 (2-12)
 Polyarticular RF- 25.5 (16-41.5) 5 (3-15.5)
 Enthesitis-related 30 (8.5-59.5) 5 (4-13.5)
C-reactive protein, mg/l 6.6 (1.9-19.7) 1 (0-4.6)
 Persistent oligoarticular 2.6 (1-10) 0 (0-1)
 Extended oligoarticular 6.4 (2.4-15) 1 (0-3)
 Polyarticular RF- 9.8 (4-27) 1 (0-6.5)
 Enthesitis-related 16.7 (7.6-52.3) 3.7 (0.9-12.6)
  1. RF rheumatoid factor, IQR interquartile range